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Rab Detection Initiative and LRRK2 Detection Initiative Supplemental Support RDI, and LCC exosome replication
… This grant builds upon the research from a prior grant: Rab Detection Initiative Study … models treated with LRRK2 kinase inhibitors. Impact on Diagnosis/Treatment of Parkinson's disease: LRRK2 and Rab … Research Grant …
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Gene Therapy Approach to Reduce Alpha‐synuclein Aggregation in a Model of Parkinson's
… protein alpha-synuclein inside brain cells. The team plans to use a gene therapy approach to insert a gene into a model … molecular, protein and behavioral measures to examine how this treatment affects the accumulation of … in the development of clinical grade viral vectors for testing in clinical trials. …
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Possible Disease-Modifying Therapy for Parkinson’s One Step Closer to Patients
November 26, 2014
… for good reason. A promising disease-modifying therapy is getting closer to reaching people with Parkinson’s. Isradipine — a … See if you are eligible for ongoing clinical trials by completing a profile on Fox Trial Finder . Watch the full …
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Optogenetic Restoration of Basal Ganglia Function to Treat Parkinson’s Disease
… Study Rationale: Optogenetics has gained wide interest as a tool to understand … unintended targets. Next Steps for Development: Successful completion of this study will generate sufficient data to … some of the newest genes did not function as we had hoped. However, we found that at least two other known agents were …
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A Conversation with Michael J. Fox: On Testing the Limits of Optimism
April 20, 2021
… Register for Webinar A Conversation with Michael J. Fox: On Testing the Limits of Optimism First Name Last Name Email Postal Code What is your primary connection to Parkinson's? ${selected} I have PD Immediate family … had PD I am a researcher, clinician or work with the PD community Other Diagnosis Date ${selected} Jan Feb Mar Apr …
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2022 By the Numbers: How MJFF’s Community Fundraisers Generated Nearly $11 Million in One Year
January 25, 2023
… Last year, our fundraising community raised over $10.8 million to benefit The Michael J. Fox Foundation (MJFF). Through … peer-to-peer fundraisers raised the bar once again. So, how did they generate over $10.8 million in one year? Let’s …