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The Michael J. Fox Foundation’s Edmond J. Safra Fellowship in Movement Disorders Continues to Expand Its Reach Globally and Trains Clinician-Scientist Leaders for A New Era of Parkinson’s Research and Care
October 19, 2023
… alumni and sustain their contributions to Parkinson’s research beyond their Fellowship, the Edmond J. Safra … annual incidence of PD among older adults in the U.S. is nearly 50 percent higher than the rate previously estimated … clinical study, PPMI; increases the flow of participants into Parkinson's disease clinical trials with its online …
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Validation of Alpha-synuclein Oligomers as Biomarker for Parkinson’s Disease
… were even higher in patients with mild PD and patients with early PD compared to the control group. The ultimate … (UPDRS off) scores, cognitive (MMSE), etc. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Rapidly advancing basic research is creating an expanding pipeline of candidate …
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Salivary Biomarkers for Parkinson's Disease
… Biomarkers are needed for assisting with the diagnosis of Parkinson’s disease (PD) and for monitoring its … that can 1) assist with PD diagnosis, particularly at the early stage of the disease when the clinical diagnosis is … develop the assays for Parkinson’s diagnosis, ideally at early stages of the disease, using saliva, as well as to …
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Analysis of LRRK2 Antibodies
… Parkinson’s disease (PD). There is therefore intense research taking place to better understand LRRK2 and its … used to measure LRRK2 from different sources. Because much research is being carried out with human and pre-clinical … the role of LRRK2 in Parkinson’s disease. Relevance to Diagnosis/Treatment of Parkinson’s Disease: We believe that …
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Software for the Analysis of Data on Parkinson's Disease Symptoms Collected Using Wearable Technology
… using wearable technology. We believe this product can help researchers, clinicians, and people with Parkinson's analyze … from smartphones and wearable technology in recent research studies. We will release the software as open … to expand and improve the software long term. Impact on Diagnosis/Treatment of Parkinson's disease: The software …
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Characterization of LRRK2 Monoclonal Antibodies in Pre-clinical Brain Tissue
… so we can design drug therapies. Antibodies are research tools that help us to map the location of proteins … idea of which brain cells LRRK2 is present in. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Understanding … rely on normal LRRK2 function. Focusing more intensive research on these areas in LRRK2 disease models (e.g. …