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Validation of ATP13a2 / PARK9 as a Target to Reduce Neurodegeneration Induced by Alpha-Synuclein
… role in Parkinson’s disease and identifying valid targets to ameliorate the neurodegenerative effects of … form of recessive Parkinsonism. ATP13a2 is most highly expressed in PD sensitive regions of the brain and in the … aiming at enhancing ATP13a2 activity. Anticipated Outcome: The successful demonstration that increased ATP13a2 …
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A ‘Going Beyond Medications’ Q&A Session with Dr. Monique Giroux
August 3, 2012
… In June, the Foundation hosted a Hot Topics call “Living with PD: Going Beyond Medications” with featured speaker Dr. … an individual's response to medicine. Diet, fatigue, blood pressure, endurance, medication side effects (sedation or …
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Use of LRRK2 and Lysosomal Biomarker Signatures to Differentiate Idiopathic and Monogenetic Parkinson’s Disease
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Survey Says: How MJFF Gathers Global Input to Guide Research
May 16, 2025
… (MJFF) pursues an aggressive research path guided by top scientists. To do so, the Foundation gathers input from … To get started, the MJFF team asked the scientific community to share ideas about targets that might have … MJFF will survey the group to get first-hand perspective on how research is translating to the clinic, as well as …
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What We Fund: $86 Million to Refine Our Understanding of Parkinson’s
February 20, 2025
… those associated with PD. One project chosen from the RFA comes from Professor Lezanne Ooi’s research at University of … identify as being disruptive is freezing of gait, where a person may feel like their feet are stuck in mud. … . To learn more about active funding mechanisms at MJFF, visit our Funding Opportunities page. David Kumbroch Senior …
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The Appendix and Parkinson's: 'It's a Piece to the Puzzle'
November 2, 2018
… 1.6 million Swedes, found that people who had an appendectomy were 20 percent less likely than those with an appendix … can undergo an appendectomy to eliminate Parkinson's risk.) Commenting on these findings, Rachel Dolhun, MD, vice … American . Hear more from Dr. Dolhun on this subject by visiting HealthDay . …