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Assessing the PINK1 Pathway in Parkinson
… different in cells from individuals with PD. Impact on Diagnosis/Treatment of Parkinson's Disease: Discovery of … Research Tool …
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DLN-101 for the Treatment of Parkinson’s Disease
… of Dln101 in the brain and plasma. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Once Dln-101 is … Research Grants …
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Combining Mass Spectrometry with Genetic and Pharmacological Approaches to Discover and Validate LRRK2 Substrates
… genetic and clinical expertise from six world leading researchers based in the United States, United Kingdom and … to new ideas and accelerate our ability to devise improved diagnosis and treatment of Parkinson’s disease in the … we generate in this project will be of great relevance to researchers as well as many pharmaceutical companies …
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Regulated GDNF Gene Therapy: a Novel Regulatory System Based on Protein Degradation
… the gene for glial-cell derived neurotrophic factor (GDNF) into the brain has the potential to protect brain cells in … in pre-clinical models of Parkinson’s disease. Relevance to Diagnosis/Treatment of Parkinson’s Disease: The GDNF … of using GDNF in this contex for further development into a clinical therapy. Progress Report We have developed …
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Symptoms and Side Effects of LRRK2 Mutation Carriers and Assessment of Factors Influencing LRRK2-related PD Expression
… our Spanish LRRK2 cohort with G2019S and R1441G mutations into the existing LRRK2 Cohort Consortium (L2CC) of people … will bring increased knowledge into possible biomarkers for early diagnosis and disease progression that may be useful not … Research Grant …
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Improving Levodopa Bioavailability and Consistency of Absorption through Co-administration of GSK962040
… "on-off" fluctuations. GSK962040 is a medication that, in research studies, has been shown to increase the speed at … before, during and after receiving the study medication. Researchers will measure participants’ levodopa levels in … that can result from delayed gastric emptying. Relevance to Diagnosis/Treatment of Parkinson’s Disease: If this …