… The appearance of these deposits is believed to be an early marker of disease. An ability to visualize and … deposits in the brains of people with PD and FTD. Impact on Diagnosis/Treatment of Parkinson’s disease:  Detection of … tau PET tracers will be made available to the PD and FTD research and therapy communities for a variety of imaging …

… Being able to detect problems with mental function at an early stage, to monitor and to reliably detect treatment … are several scales that record cognitive impairments, but researchers do not know which is best, since they have not … will be judged against a composite measure, which takes into account how the study participant is doing as compared …

… Our recent work suggests that inflammation may be increased early in the course of PD. Hypothesis: We aim to replicate … that a panel of inflammatory markers is increased early in the course of Parkinson's. Study Design: We will … and those that have been diagnosed with PD. Impact on Diagnosis/Treatment of Parkinson's Disease: Identifying …

… PPM1H will be further characterized and studied. Impact on Diagnosis/Treatment of Parkinson’s disease:  This work has … pharmaceutical companies to further develop the compounds into potential drug candidates. … Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies …

… we will inject different doses of the therapeutic nanobody into the brain and examine its penetration and distribution. … normal function of these neural circuits. Impact on Diagnosis/Treatment of Parkinson’s disease:  Abnormal … Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies …

… this study would allow a first, “lead”, molecule to advance into preclinical development toward an Investigational New … Fall 2021 RFP: Accelerating Early Proof-of-Concept Testing of Promising PD Therapies …