… 30 patients with PD and 30 normal controls. Relevance to Diagnosis/Treatment of Parkinson’s Disease:                 …      Identification of biomarkers is an important task for early diagnosis, as well as evaluation of potential new treatments … Research Grant …

… correlate with the cognitive and movement symptoms in early versus advanced Parkinson’s disease.  Study Design: We will study 25 individuals with early to moderate Parkinson’s disease who show no … and cognitive symptoms in each participant.   Impact on Diagnosis/Treatment of Parkinson’s Disease: DaTScan is …

… brains using a safe virus. This will help us study the early changes in the brain that happen in Parkinson's … Hypothesis: We believe that putting extra alpha-synuclein into each model brains will cause movement problems and … the protein affects brain health and movement. Impact on Diagnosis/Treatment of Parkinson’s disease: This project …

… evidence, we can begin translating these insights into products that can improve the clinical management of … of PD: the time between symptom onset and formal clinical diagnosis. This study proposes to leverage the biospecimen … data resource will accelerate the generation of insights into the mechanisms and signatures of PD, with a particular …

… This grant builds upon the research from a prior grant: Studies on the effects of … of a combination of laboratory markers for the better and early diagnosis and to possibly objectively measure progression of … MJFF Research Grant …

… This grant builds upon the research from a prior grant: Optimization of Nigrostriatal … unilateral injection of preformed alpha-synuclein fibrils into pre-clinical models. We also observed a distinct … to degeneration, could provide an important biomarker of early PD. …