… the presence of a Miro1 defect will serve as an important early diagnostic and prognostic biomarker of PD to … assays to translate findings from patient skin cells into an assay using patient white blood cells. Taking a … use in future large-scale and clinical studies. Impact on Diagnosis/Treatment of Parkinson’s disease:  Development of …

… This grant builds upon the research from a prior grant: Peripheral Administration of … administered following experimental procedures. Impact on Diagnosis/Treatment of Parkinson's Disease: Successful … a path forward for a 60-day biomarker-directed trial in early stage PD. Next Steps for Development: FPRT Bio would …

… parasympathetic and sympathetic nervous systems. Recently, early-occurring Parkinson’s disease-related Lewy pathology … disease and how the development of cardiac pathology fits into the neuropathological staging system for the brain … large portions of the human nervous system.  Relevance to Diagnosis/Treatment of Parkinson’s Disease: The results of …

… of WATCH-PD, a 12-month study of digital measures in early PD, with longitudinal remote digital assessments and … digital measures that are sensitive to change over time in early PD. Study Design:  We will recruit participants from … and wear a smartwatch for 1 week every 3 months. Impact on Diagnosis/Treatment of Parkinson’s disease:  Identifying …

… attention or difficulty following plans can occur very early in the disease process, even before the emergence of … with (and may give rise to) cognitive impairments early in the development of PD. Study Design:  We will study … connections linking the cortex with the striatum. Impact on Diagnosis/Treatment of Parkinson’s disease:  This study …

… neurons have degenerated will be observed.  Relevance to Diagnosis/Treatment of Parkinson’s Disease: Presently, … Research Tool …