… Parkinson’s disease (PD) damages brain connections early on, linked to accumulation of a protein called … reliability for tracking brain changes in PD. Impact on Diagnosis/Treatment of Parkinson’s disease:  In PD, early damage happens at the connections between brain cells, …

… Lewy bodies led to conflicting results. This collaborative research project will test several immunohistochemical … sensitive and specific method will be adopted. Relevance to Diagnosis/Treatment of Parkinson’s Disease:                 … help in developing a reliable biomarker for PD. Parkinson’s researchers seek a validated biomarker for earlier, …

… they compare with the imaging results over time. Impact on Diagnosis/Treatment of Parkinson’s disease: If successful, … with high resolution camera has the potential to refine early diagnostic imaging enabling us to detect dopamine cell … in PD. Incorporating high-resolution imaging systems into ongoing and future studies will be a step towards …

… be tested for GBA mutations and GCase activity. Impact on Diagnosis/Treatment of Parkinson's Disease: It is unclear to what degree GCase activity changes in the early stages of PD. If changes are present early on (in RBD, for example), the GCase pathway could be …

… seen frequently in Parkinson’s disease (PD) would improve diagnosis of the disease and identify PD subtypes for more … the results of the motor and cognitive tests. Relevance to Diagnosis/Treatment of Parkinson’s Disease:   A measurement … each potential markers of PD heterogeneity, which could aid early diagnosis and assessment of disease-modifying …

… to best measure disease progression prior to traditional diagnosis of PD. Hypothesis:  We hypothesize that … at high risk. Study Design:  Following the conference, the researchers and advocates will prepare three integrated … are at risk of or manifesting the symptoms of PD. Impact on Diagnosis/Treatment of Parkinson’s disease:  The …