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Intranasal GDNF for Parkinson's Disease: Next Steps in Preclinical Development
… a treatment for Parkinson’s disease. However, getting GDNF into the brain has proven to be an insurmountable obstacle. … in the models at the end of the study. Relevance to Diagnosis/Treatment of Parkinson’s Disease: GDNF cannot … the brain to stop Parkinson’s disease progression in its early stages. If this route of administration proves …
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Using Deep Brain Stimulation to Understand and Treat Dystonia Associated with Parkinson’s Disease
… that 40 percent of people with PD experience dystonia as an early symptom or complication of treatment. Deep brain … and treat resistant motor symptoms in the legs. Impact on Diagnosis/Treatment of Parkinson's Disease: This study will help researchers and clinicians better understand dystonia …
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A Global Search for People with a Rare, Inherited Form of Parkinson's Disease
… cause inherited Parkinson's disease (PD) that starts at an early age. This type of Parkinson's accounts for roughly 13 … and opportunities for data and sample sharing. Impact on Diagnosis/Treatment of Parkinson's disease: It is likely … establish a large, international network of clinicians and researchers working on PRKN - and PINK1 -associated PD. It …
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Discovery of Selective PET Imaging Agents for Tauopathies and Alpha-Synuclein
… This grant builds upon the research from a prior grant: Alpha-synuclein/Tau Imaging … features of Parkinson’s and FTD and are believed to be early disease markers. The ability to visualize and quantify … of living Parkinson’s and FTD participants. Impact on Diagnosis/Treatment of Parkinson’s Disease: Early detection …
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MJFF Recruitment Centers of Excellence
… a variety of strategies which might increase enrollment into trials and studies. Hypothesis: This study hopes to better understand barriers to participation in research for PD and to address those barriers. We … through changes in the way research is performed. Impact on Diagnosis/Treatment of Parkinson's disease: The main goal of …
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Near Infrared Chronic Intracranial Illumination for Neuroprotection in Parkinson's Disease
… We will develop a prototype to deliver continuously into patients’ brains infrared light to slow down the loss … the effect of this intracranial illumination. Relevance to Diagnosis/Treatment of Parkinson’s Disease: … of a clinically feasible device to be implanted at early stages of Parkinson’s disease. Posters and …