… Study Rationale: Previous research has shown higher levels of the c-Abl protein are … the role of this protein in Parkinson's, it showed early promise as a potential therapeutic target. A small … Additional Support: MJFF has collaborated with Van Andel Research Institute (VARI) and The Cure Parkinson's Trust …

… these changes will ultimately allow an ophthalmological diagnosis and assessment of PD severity.   Study Design: We … amount of glial “scar tissue” that is present. Impact on Diagnosis/Treatment of Parkinson’s Disease:              … the changes seen could potentially be used to improve the diagnosis of PD and to evaluate if PD treatments in …

… This grant builds upon the research from a prior grant: Cytokine Production by Adaptive … Design:  The PD patient population consists of two groups: early-stage idiopathic PD (less than 2 years since clinical diagnosis; n=50) and mid-stage idiopathic PD (diagnosed more …

… whether it is possible to detect Parkinson’s in the very early stages from voice recordings. Project Description: The … so, at what precise level of symptom severity. Relevance to Diagnosis/Treatment of Parkinson’s Disease:                 … to learn something about whether voice changes are an early sign of the condition. Finally, we will know by the …

… This grant builds upon the research from a prior grant: Insights into LRRK2 Kinase Inhibitors Study Rationale: Our previous … genes that may underlie the cellular response. Impact on Diagnosis/Treatment of Parkinson’s Disease: Studies of this … Research Grant …

… to monitor symptoms and quality of life in individuals with early, untreated Parkinson’s disease (PD). This planning … patient recruitment and IRB submission. Impact on Diagnosis/Treatment of Parkinson’s disease:  Digital tools … Research Grant …