-
Knowledge, Responsibilities, and Peer Advice from Care Partners of Patients with Parkinson Disease Psychosis
January 4, 2021
… informal support networks. The objective of this study was to characterize CP responsibilities, sources of support, and … Only 16 (11%) learned about PDP from a physician; communication challenges included perceived embarrassment or … Few CPs advocate for medications to control PDP, instead preferring non-pharmacological management strategies. Peer …
-
Focused Ultrasound to Treat Parkinson’s Symptoms on Both Sides of the Body Approved
July 14, 2025
… for the management of Parkinson’s-related movement, or motor, symptoms. The approval is an advance in focused … tremor, and in 2021 for additional motor symptoms and complications, like dyskinesia and ups and downs in symptom … whether you’re a candidate and guide you on when and where it may become available. David Kumbroch Senior …
-
Characterization of a Novel Strategy to Target LRRK2 and Its Downstream Signaling Pathway
… Genetic mutations that activate LRRK2 are linked to familial Parkinson’s disease (PD). However, no clinically … In this study, we will develop and characterize novel compounds that inhibit either LRRK2 itself or a key … successful, the results will validate new LRRK targets and present a novel strategy for the development of PD …
-
Blocking Inflammasome-induced Neuroinflammation in Parkinson's Disease with a Potent, Orally Available Small Molecule
… in pre-clinical models of the disease. We hope this treatment could halt or even reverse Parkinson's progression. … so we will design and test new molecules that act the same way, but are more drug-like, last longer, and could be … pill to stop brain inflammation. Impact on Diagnosis/Treatment of Parkinson's Disease: Labeled versions of the small …
-
Optogenetic Restoration of Basal Ganglia Function to Treat Parkinson’s Disease
… Study Rationale: Optogenetics has gained wide interest as a tool to understand … neuronal functions. This will first be tested in a pre-clinical PD model in which symptoms develop after … unintended targets. Next Steps for Development: Successful completion of this study will generate sufficient data to …
-
What It's Like to Volunteer for a Clinical Research Trial
January 20, 2015
… Read some excerpts below, and see the full article to learn more about what it's like to participate. The advancement of drug therapies into … in participating in PD clinical trials but don't know where to start? Learn more on our clinical trials hub or …