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Parkinson's Disease Biomarker Discovery and Verification Using Multiple Reaction Monitoring
… patient and control samples in a future study. Impact on Diagnosis/Treatment of Parkinson’s Disease: A biomarker … that are associated with PD could eventually serve as an early diagnostic, a means of measuring disease progression … Research Grant …
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Identifying Protein Changes Associated with Parkinson’s Disease: Proteomics Public Data Compilation
… approach, could reveal information that would facilitate diagnosis or targeted treatments for these disorders. … made easily accessible to other investigators. Impact on Diagnosis/Treatment of Parkinson’s disease: This analysis … Research Grant …
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(SUPPLEMENT) The Foundational Data Initiative
… This grant builds upon the research from a prior grant: Using a Systems-based Approach … by subjects from the PPMI will be cultured and grown into nerve cells similar to those found in the human brain. … cellular and molecular level to cause disease. Impact on Diagnosis/Treatment of Parkinson’s disease: This work has …
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Automated Platform for Standardizing and Validating GBA1 Human iPSC Models To Accelerate Mechanistic and Therapeutic Discovery in Parkinson’s Disease
… at two different locations, using independent materials and researchers. We will share detailed cell generation … datasets with the PD research community. Impact on Diagnosis/Treatment of Parkinson’s disease: While … across laboratories. Next Steps for Development: Insights into GBA1 mutations have the potential to reveal biological …
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PARK14-dependent SOCE and Sporadic Parkinson’s Disease
… This grant builds upon the research from a prior grant: PARK14: Validation of a New … stem cell-derived dopaminergic neurons. Relevance to Diagnosis/Treatment of Parkinson’s Disease: … and Parkinson's Disease. Poster presented at: Gordon Research Conference; 2015. …
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Antibody Development for Modified Parkin Proteins Identified in the Human Brain
… Parkinson's. In doing so, we will gain important insight into the normal age- and disease-associated metabolism of … , which will further inform preclinical as well as clinical research. Impact on Diagnosis/Treatment of Parkinson's Disease: Parkin-specific …