… quality measures and engage in active discussion. Impact on Diagnosis/Treatment of Parkinson’s Disease:  The quality … will generate large datasets that can provide insights into treatment patterns and outcomes for DBS. By collecting … Research Grant …

… lab has introduced the gene for human alpha-synculein into the fly brain and has found that this causes a walking … We will now repeat this with human brain cells. Impact on Diagnosis/Treatment of Parkinson’s disease: If the SCAMPs … Research Grant …

… hope that pharmacological antagonism of this pathway with rasagiline, in combination with antagonism of calcium … isradipine in which a subset of the patients were taking rasagiline. Hypothesis: Monoamine oxidase-dependent dopamine … them to create stress. Third, the interaction between rasagiline (an FDA-approved inhibitor of monoamine oxidase) …

… This grant builds upon the research from a prior grant: LRRK2 Variation in Parkinson's … the global impact of LRRK2 in disease. Importance of This Research for the Development of a New PD Therapy: … each new penetrant mutation or risk factor we gain insight into the functional pathomechanisms underlying disease …

… This grant builds upon the research from a prior grant: Structural Characterization of … We will also include the Parkinson’s-associated variants into our structural project. Structures of these … and thereby enzymatic activity of GCase. Importance of This Research for the Development of a New PD Therapy:     As …

… to derive a generally valid method for further clinical and research use of OCT. Relevance to Diagnosis/Treatment of Parkinson’s Disease : Parkinson … (PD) is a progressive neurodegenerative disease. Current research attempts to find protection against progression. …