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Analysis of the Role of PPN Neurons in Postural Disturbances in a Model of Parkinson's Disease
… This grant builds upon the research from a prior grant: Development of a Model of … funded by The Michael J. Fox Foundation for Parkinson’s Research was to unravel the role of non-dopaminergic lesion … study. Gait and postural deficits obtained after MPTP intoxication will be compared with those observed after PPN …
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Feasibility of Screening for Parkinson's Genetic Risk Factors in People of Asian Ancestry
… the feasibility of engaging PD patients of Asian descent in research, including genetic screening. Study Design: The … 2) To assess PD awareness and attitudes regarding medical research and genetic testing among people with PD of Asian … leaders, health systems and media outlets. Impact on Diagnosis/Treatment of Parkinson's Disease: Involving people …
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Analysis of the LRRK2-Rab Signaling Pathway
… This grant builds upon the research from a prior grant: Rab Detection Initiative … Grant: The highlight of our teams' recent MJFF funded research has been the discovery of the key physiological … that is related to Parkinson's disease. Importance of This Research for the Development of a New PD Therapy: The …
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Targeting Serotonin Transporters for the Treatment of Levodopa-induced Dyskinesia Supplement
… This grant builds upon the research from a prior grant: Targeting Serotonin … on previous work with SSRIs for the reduction of LID. Researchers identified a FDA-approved compound from Forest … LID at therapeutically viable doses. Importance of This Research for the Development of a New PD Therapy: …
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DAT Imaging in Ashkenazi Jews (AJ) LRRK2 Gene Carriers - a consortium proposal
… changes in the brain even before any PD symptoms occur. Early detection of brain imaging changes will help to … compared to those without the gene mutation. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Utilizing DAT … MJFF Research Grant …
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Enhancing the Clinical Utility of Data-Driven Parkinson’s Subtypes with Knowledge Distillation and Visualization
… This grant builds upon the research from a prior grant: Analyzing Data from the … limitations to their clinical utility. The goal of this research is to develop knowledge distillation and … interface to understand the PD subtypes. Impact on Diagnosis/Treatment of Parkinson’s Disease: The research in …