… Study Rationale: Although the precise mechanism(s) of neurodegeneration in Parkinson's … suggests that neuroinflammation is an important contributor. In this study, we will use pre-clinical models of PD to … models of PD that have significant inflammatory components. Existing drugs/compounds that target the …

… Objective/Rationale: Autonomic disturbances are common symptoms of Parkinson’s … weight of different autonomic symptoms in PD and their prevalence in healthy non-manifesting carriers. To …

… Study Rationale: LRRK2 inhibitors are among the most promising in the current generation … potential novel treatments for Parkinson's disease (PD). In pre-clinical models, long-term treatment with LRRK2 … and markers of PD in the brain. After the evaluation is complete, we will examine the lungs of the models for any …

… by more than 1,500 members of the Parkinson’s community who are finding their own summits through Tour de Fox and … has been overwhelming. We’ve had so many families meet us who have driven three, four, even seven hours each way just … Tour de Fox and critical PD research. In North Dakota , Janet and Neil Zetah joined the Tour for not one but two …

… After months of planning, Team Fox member Anna Wolfe stood before a crowd of over 200 local supporters on October 18 and warmly welcomed them to the 9th Annual North Shore Walk for … Parkinson’s Disease . A homegrown effort founded in 2007 with just 25 attendees, this family-friendly 3-mile walk …

…                Gait and balance disorders are the primary motor disability in advanced Parkinson’s disease (PD). These … deformable atlas for the human brainstem, as we have done previously for the human basal ganglia. We will test the efficacy of DBS of two different targets in the …