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Generating Patient-Specific Induced Pluripotent Stem Cells to Study Parkinson's Disease
… neurons. Because these differences can potentially be used to discover novel drugs for Parkinson’s disease, we would … the deficiencies of dopamine neurons with parkin mutations, compared to normal neurons. Relevance to Diagnosis/Treatment … the study will allow us to screen for novel therapeutic targets for Parkinson’s disease using cells that are most …
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Utilizing Transcriptional Pathways to Enhance Mitochondrial Health in Models of Parkinson’s Disease
… Neurons of the substantia nigra are particularly vulnerable to cell death in Parkinson’s disease (PD). One potential … potential to identify a biochemical pathway that can be targeted to prevent and/or slow the progression of neuronal cell loss in PD. Anticipated Outcome: If we find that this particular molecule is …
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Identifying and Pilot Testing Best Practices for Sharing Amyloid PET Research Information with Individuals Living with Lewy Body Diseases
… opinions about receiving research test results that relate to a person’s known diagnosis, like Parkinson disease. It … different kinds of research test results. This will let us get opinions from a broader group of people. We will then … test results with participants. Research can then study how people respond to learning expected and unexpected test …
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In One Month, Thousands Rally to #FoxItForward for a Cure and Raise $1M
November 30, 2016
… Starting November 1, we asked our community to grab the megaphone and rally their family and friends to … their best "unselfies," many of our crowdfunders proudly showed off their support on social: Until a cure is …
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MJFF Announces $1.2 Million in Funding to Advance Development of Drug Targets For PD
August 1, 2007
… for Parkinson’s Research (MJFF) announced $1.2 million in total awards to four research teams working to advance … plc (NYSE: ELN), a neuroscience-based biotechnology company. "For successful translation into real-world PD … see if they can reduce deficits seen in animal models. Neil Howell, PhD, of San Diego-based MIGENIX Corporation will …
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Targeting Rubicon to Restore Lysosomal and Autophagic Health in LRRK2 Mediated Parkinson’s Disease
… develops in part because brain cells lose the ability to clear away damaged proteins and cell parts, leading to … cell death. A gene called LRRK2, which is one of the most common genetic causes of Parkinson’s, makes this problem … Rubicon levels using modern genetic tools, I will measure how well cells can recycle damaged proteins, clear toxic …