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Inhibition of Striatal-enriched Phosphate (STEP) to Improve Parkinson-related Cognitive Dysfunction
… This grant builds upon the research from a prior grant: Inhibition of Striatal-Enriched … cognitive function in these models. Importance of This Research for the Development of a New PD Therapy: This is … Research Grant …
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The Role of LRRK2 Activity in Inherited Parkinson's Disease
… This grant builds upon the research from a prior grant: Role of GTPase Activity in … can stop or slow neurodegeneration. Importance of This Research for the Development of a New PD Therapy: In the … Research Grant …
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Parkinson’s Disease Treatment Evaluation and Access Strategy: Phase 1
… J. Fox Foundation (MJFF) have historically focused on research to understand, measure, and treat Parkinson’s disease (PD). MJFF is now seeking to expand its research agenda to examine pathways for evaluating and … innovative PD treatment evaluation and access. Impact on Diagnosis/Treatment of Parkinson’s disease: This project …
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(Supplement) Self-reported Perceptions and Self-reported Outcomes on Motor and Non-motor Symptoms in the Parkinson's Disease Continuum: A Systematic Review of Mixed Methods
… This grant builds upon the research from a prior grant: Self-reported Perceptions and … with Parkinson's Disease and their care partners. Impact on Diagnosis/Treatment of Parkinson’s disease: This study has the potential to impact the delivery of clinical and research plans that meet end-user preferences and needs by …
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Evaluation of ANAVEX2-73 (blarcamesine) in Participants with Parkinson’s Disease
… (also known as blarcamesine), which previous research has shown helps improve behaviors as well as … with Parkinson’s disease. Study Design: In this study, researchers will give ANAVEX2-73 (blarcamesine) to up to 24 … sure it is safe and has minimal side effects. Impact on Diagnosis/Treatment of Parkinson’s Disease: This …
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Studying the Parkin Protein in New Pre-Clinical Models
… This grant builds upon the research from a prior grant: Evaluation of the Parkin … to be active. In contrast, this pathway is active in early-onset PD, but does not function as it should. We now … in pre-clinical models of Parkinson's. Importance of This Research for the Development of a New PD Therapy: This work …