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The Transcription Factor Nrf2 as a Target to Reduce Neurodegeneration and Neuroinflammation in Parkinson's Disease
… in PD pathology that may result from an inadequate response to toxic, oxidant or inflammatory agents in the basal … to these agents, the so-called phase II response. There are compelling evidences from basic and clinical studies … we explore a new approach to neuroprotection based on targeting the transcription factor Nrf2 pharmacologically with …
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Speeding up to Slow Parkinson’s Down: New Study Shows Exercise Delays PD Progression
March 27, 2017
… strengthen the heart and bones, boosts mood and energy, and combats illness. For people with Parkinson's disease (PD), … and increasingly affect quality of life. A recent study showed that exercising just 2.5 hours per week could help … , published in the Journal of Parkinson's Disease , monitored the self-reported exercise of more than 3,400 people …
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National Football League Donates Record $30 Million to Research on Head Trauma
September 6, 2012
… New Study Linking League Players to Higher Risk of Death by Alzheimer’s and ALS Released on … a result of certain diseases that damage brain cells when compared with the general population. Their risk of dying … injuries and dying from Parkinson’s disease (PD) was not shown to be significant in this particular study, work …
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Parkinson’s Disease Clinical Trial Results to Be Presented at AAN Annual Meeting
March 18, 2013
… This week, more than 12,000 are expected to attend the American Academy of Neurology 's (AAN) Annual … pressure, as well as in dizziness and lightheadedness, when compared to placebo after one week of treatment. However, when tested over a period of more than a week, the …
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My Research Journey: From Falling Out of Bed to Participating in a Parkinson’s Study
September 26, 2022
… Otis Peeples and his wife, Linda “I’ve hurt myself falling out of bed, while still asleep, and that is … own risk for Parkinson’s disease. PPMI collects information from participants with and without Parkinson’s over time. Otis has been completing tests and sharing biological samples (e.g., …
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Cytokine Production by Adaptive Immune Cells in Parkinson’s Disease: Response to Diverse Biological Stimuli
… disease. Our study will produce proteins called cytokines that play a role in the immune response to determine … be used to measure Parkinson’s or point to a new way to stop the disease. Hypothesis: We hypothesize that people … production by adaptive immune cells. We will explore how to dampen pro-inflammatory responses in these cells. …