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Pharmacological Targeting of Inflammasome Activation Mechanisms in Synuclein Models of Parkinson's Disease
… This grant builds upon the research from a prior grant: Pharmacological Targeting of … system and chronic brain inflammation. Importance of This Research for the Development of a New PD Therapy: This … Research Grant …
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Development of a Biomarker Assay for Oxidized DJ-1 in Parkinson’s Disease
… This grant builds upon the research from a prior grant: Collaborative Validation of … Mutations in the DJ-1 gene cause an early-onset form of Parkinson’s disease (PD). The DJ-1 … assays and test them in a PD and control cohort. Impact on Diagnosis/Treatment of Parkinson’s Disease: …
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Role of LRRK2 in Alpha-synuclein-induced Neurodegeneration: Supplement
… This grant builds upon the research from a prior grant: Role of LRRK2 in … usage of the Pfizer A inhibitor. Importance of This Research for the Development of a New PD Therapy: It … Research Grant …
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Targeting of the Raphe-Cortical Pathway to Reduce Levodopa-Induced Psychosis
… a chemical that transmits messages between nerve cells. Our research will examine how changes in the brain’s serotonin … movement disorders, or dyskinesia. Impact on Diagnosis/Treatment of Parkinson’s Disease: Successful … work will address a gaping hole in the Parkinson’s disease research field by identifying brain circuits through which …
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GBA Meta-analysis Initiative: Charting a Path to Success for Clinical Trials in Patients with GBA-PD
… This grant builds upon the research from a prior grant: Genetic Predictors of … novel targets for tailored therapies. Importance of This Research for the Development of a New PD Therapy: This … Research Grant …
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Investigation of LRRK2 as a Regulator of Dendritic Cell Function
… This grant builds upon the research from a prior grant: Investigation of LRRK2 as a … in those taking these treatments. Importance of This Research for the Development of a New PD Therapy: A new … Research Grant …