-
Inhibition of Striatal-Enriched Phosphatase (STEP) to Improve Parkinson-Related Cognitive Dysfunction
… will examine the pharmacokinetic profile of a STEP inhibitor drug as a potential precursor to efficacy studies. … be performed using intravenous administration of drug for comparative purposes. Impact on Diagnosis/Treatment of … cognitive functioning. Final Outcome This pilot study has shown the bioavailability of the novel Striatal-Enriched …
-
Targeting the Blood-brain Immune Axis to Prevent Progression of Parkinson’s Disease
… from the rest of the body, including the blood, might become dysfunctional over the course of Parkinson’s disease (PD). How this barrier becomes compromised is unknown. However, its breach could allow brain cells to come in contact with detrimental blood-borne factors, …
-
Targeting the Blood-brain Immune Axis to Prevent Progression of Parkinson’s Disease
… from the rest of the body, including the blood, might become dysfunctional over the course of Parkinson’s disease (PD). How this barrier becomes compromised is unknown. However, its breach could allow brain cells to come in contact with detrimental blood-borne factors, …
-
The Michael J. Fox Foundation for Parkinson's Research to Fund Search for Parkinson's Biomarker
April 8, 2002
… Research (MJFF) announces a $2 million research initiative to develop or validate conclusive diagnostic tests, or … on its cause." The biomarker initiative is a direct outcome of discussions held during MJFF's ongoing series of … high-impact areas of Parkinson's research and determine how the MJFF can most effectively advance the state of the …
-
siRNA Screen of Microglia to Identify Neuroprotective Drug Targets in Parkinson´s Disease
… Neuroinflammation is a fundamental process contributing to the death of neurons in Parkinson´s disease (PD). During … Diagnosis/Treatment of Parkinson’s Disease: The successful completion of our study will provide us with a dataset of … This is the beginning for a comprehensive understanding of how microglia deactivation is regulated inside the cell, so …
-
Sniff Test: Surprising New Learnings about Smell Loss and Parkinson’s (Webinar Audio) Transcript