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A Pre-clinical Alpha-Synuclein Model of Parkinson's Disease
… vector that overexpresses the gene for alpha-synuclein into the brains of non-human primate pre-clinical models of … counts of alpha-synuclein inclusions. Relevance to Diagnosis/Treatment of Parkinson’s Disease: To date, MPTP … MJFF Research Grant …
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Targeting Glia in PD with Novel Anti-inflammatory Therapeutics
… test their suitability for oral drug delivery. Relevance to Diagnosis/Treatment of Parkinson’s Disease: … (Oct) Michael J. Fox Foundation for Parkinson's Disease Research. Invited plenary speaker at the third annual … Research Grant …
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fMRI of First Degree Relatives of LRRK2 Positive PD Patients
… in Parkinson’s disease (PD) patients who recently converted into a diseased state by comparing carriers to non carriers … and correlated to behavioral data collected. Relevance to Diagnosis/Treatment of Parkinson’s disease: The G2019S … MJFF Research Grant …
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Region-specific Effects of Pathology and Vocal Training
… deficits are common in Parkinson’s disease. They occur early in the disease process, are progressive in nature, and … in the cranial sensorimotor system specifically results in early vocalization deficits and represents an early disease … early therapeutic option in Parkinson’s disease. Impact on Diagnosis/Treatment of Parkinson’s disease: …
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PD Pre-clinical Model Repository
… by importing new models that will be available to the research community. Project Description: The JAX PD repository distributes specialized models that enable researchers to inactivate genes in specific neuronal cells … papers that describe the pre-clinical model. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Preclinical …
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Identifying Markers of PD Onset and Progression in a Prospective Cohort of Patients and ASymptoms & Side Effects Carriers of LRRK2 Mutations
… collected at the Salpêtrière brain bank. Relevance to Diagnosis/Treatment of Parkinson’s Disease: No treatment can … Research Grant …