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Brain Disease Research Organizations Pledge $2 Million USD to Uncover Similarities and Differences across Spectrum of Disorders
July 26, 2018
… Applications accepted through September 10, 2018 Open to academic and industry researchers Providing up to … will offer $2 million USD (£1.5m, $2.6m CDN) for projects comparing Alzheimer's, Parkinson's and other … populations and possible treatments. While each condition shows a distinct clinical profile, research has hinted at …
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FOX FOTO FRIDAY: Team Fox Young Professionals of NYC Welcome Michael back to TV
September 27, 2013
… Team Fox Young Professionals of New York City headed to Tribeca Cinemas to host a fun-filled premiere party in celebration of 'The … far in support of MJFF. While a large portion of proceeds come from their Annual Sunday Funday event, held each April, …
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Using Powerful Metabolomic Methods to Identify Blood-based Biomarkers of Early-Stage Parkinson's Disease
… Study Rationale: Metabolomics is an approach to studying molecules that are products of metabolism. Using … models of Parkinson's disease (PD). It allowed us to distinguish between models of early-stage Parkinson's and … healthy models of the same age. In this study, we aim to test if the metabolic fingerprint we identified is also …
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Inhibition of c-Abl Tyrosine Kinase as a Novel Therapy to Prevent PD Progression
… Mutations in the parkin gene cause early-onset autosomal recessive PD. We have discovered that parkin is … by NS-187 (Innovive, New York) as a possible therapeutic target for reducing the progressive neuronal loss during PD by … The use of c-Abl inhibitors might become an effective therapy to prevent dopaminergic cell loss …
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Combining Mass Spectrometry with Genetic and Pharmacological Approaches to Discover and Validate LRRK2 Substrates
… This grant builds upon the research from a prior grant: Combining Mass Spectrometry with Genetic and Pharmacological Approaches to Discover and Validate LRRK2 Substrates Study Rationale: … inhibitor treatment. Next, we will use mass spectrometry (test that sorts chemicals) to measure changes in cellular …
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Using Antibodies to Confirm Sticky Alpha-synuclein as the Cause of Parkinson's Disease
… Parkinson's disease (PD), but it is unclear what prompts it to clump. Researchers believe that in PD the structure and … and act as a label -- to study alpha-synuclein that has become sticky but not yet started to clump. Combined with … on Diagnosis/Treatment of Parkinson's disease: Knowing how the neurodegenerative processes in Parkinson's disease …