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Regulation of LRRK2 Membrane Association
… with cellular membranes. These LRRK2 variants may be useful research tools to discover novel therapies for Parkinson’s … on inhibiting LRRK2-mediated neurotoxicity. Relevance to Diagnosis/Treatment of Parkinson’s Disease : Because the … mutations. Anticipated Outcome : We anticipate developing research tools and advancing basic scientific understanding …
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Just in Time Pre-clinical Resource for Evaluating Symptoms & Side Effects and/or Dyskinesia Treatments
… strategies in a time and cost efficient way. Relevance to Diagnosis/Treatment of Parkinson’s Disease: This proposed research will accelerate the testing of novel Symptoms & … MJFF Research Grant …
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Predicting Parkinson’s Disease with Smartphone Data
… as an aid to clinicians and patients alike. Relevance to Diagnosis/Treatment of Parkinson’s … to supporting clinical and self-management of PD. Further research will investigate how to make the data more useful … MJFF Research Grant …
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GeneGo LRRK2 Pathway Map - Laura Brovold (GeneGo/Thomson Reuters)
… annotated biomarkers for Parkinson’s disease. Relevance to Diagnosis/Treatment of Parkinson’s Disease: After decades of … disease analysis platform primarily designed for disease researchers working on drug discovery and diagnostics. … MJFF Research Grant …
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Identification of the Parkin-binding Domain for SLP-2 as a Potential Therapeutic Target Supplement
… This grant builds upon the research from a prior grant: Identification of the … from patients with parkin mutations. Importance of This Research for the Development of a New PD Therapy: We … Research Grant Supplement …
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Multiculturalism, Reported Cognitive Complaints and Predictors of Cognitive Decline Following Deep Brain Stimulation
… reported by individuals and their family are used for PD diagnosis. We showed that several of these objective tasks … the potential influence of multiculturalism. Impact on Diagnosis/Treatment of Parkinson’s disease: Our findings … in individuals’ subjective reports, improving the diagnosis of cognitive decline. Our results will also …