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Risk Factors for Parkinson’s Disease Among Participants in the Black Women’s Health Study
… asked to report whether they had ever received a medical diagnosis of PD. We will confirm these self-reported cases … and suspected factors with the risk of PD. Impact on Diagnosis/Treatment of Parkinson’s disease: The proposed … and PD risk factors in Black women and help to reshape PD research, prevention strategies and the clinical management …
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Ask the MD: Predicting How Parkinson's Will Progress
April 11, 2019
… behavior disorder ) they had, and how severe they were. Researchers also calculated the time from diagnosis to end … findings, the researchers separated people with Parkinson's into three subtypes at diagnosis to predict future … (PPMI) follows people at-risk of Parkinson's and from the early stages of disease to better understand early …
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A Strategy to Develop a Radiotracer Targeting Alpha-Synuclein
… plan to test this radiotracer in studies of both healthy research subjects and PD patients. Relevance to … alpha-synuclein is deposited in nerve cells in PD very early in disease and appears to progressively increase, a … synuclein. The lead peptide has been labeled and injected into non-human primates scanned with SPECT. Preliminary data …
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Discovering Ocular Biomarkers of Parkinson’s Disease
… Study Rationale: Early detection of Parksinson’s disease (PD) leads to … accurate in the early stages of the disease. Recent research has shown that subtle changes in the retina and the … may provide a simpler and more accurate means of early diagnosis. Although these changes can be seen in images …
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Physiological and Pathological Implications of the Unique Subcellular Distribution of LRRK2
… pre-clincal models of Parkinson’s disease. Relevance to Diagnosis/Treatment of Parkinson’s Disease: … MJFF Research Grant …
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Validation of Enzymatic Activity and Neuropathology in G2019S LRRK2-induced Dopaminergic Neurodegeneration in a Pre-clinical Model of Parkinson's Disease
… LRRK2 expression in a pre-clinical model. Relevance to Diagnosis/Treatment of Parkinson’s Disease: These studies … MJFF Research Grant …