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Informing Clinical Decision Making in the Pre-motor Period of Parkinson Disease
… Objective/Rationale: Currently, the diagnosis of Parkinson disease (PD) relies on recognition of … process generates clinical decision rules physicians and researchers can use for categorizing people according to … tract and sleep centers of the brain are affected early in PD, while areas affecting cognition and psychiatric …
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Alpha-synuclein Effects on Gut-brain Circuits and Pre-motor Symptoms in Parkinson’s Disease
… as gender and menopause affecting this spread, resulting in early symptoms such as sleep disorders seen in humans before … a novel animal model that mimics human menopause. Impact on Diagnosis/Treatment of Parkinson’s Disease: The gene therapy … our experience to take any effective gene therapy agents into larger animals to examine non-invasive gut gene …
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“Good Night” Starts with a Good Day: Getting Your Best Sleep with Parkinson’s (Ask the MD Video)
March 25, 2024
… falling sleep, or insomnia; wake up during the night or too early in the morning; act out your dreams while asleep, … our new video with the five ways to invite better sleep into your life. Or, if you want to watch the full video … good sleep – and let you live your best life daily. Help researchers understand the connection between sleep and …
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Peripheral Benzodiazepine Receptor: An In Vivo Biomarker of Parkinson's Disease
… The goal of the proposed studies is to validate an early marker of Parkinson's disease (PD) that may be able to … protein, the peripheral benzodiazepine receptor, as an early and sensitive indicator of inflammation and … non-invasively in the living human brain. Early diagnosis of PD would be advantageous in testing therapeutic …
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What We Fund: $40.2M Toward Tools to Measure Parkinson’s and Therapies to Treat It
October 25, 2024
… and increase awareness of PD resources and clinical research opportunities. See full list of MJFF funded … cellular functions, including the flow of calcium ions into the brain. Studies have shown that mitochondria can … with different stages of Parkinson’s disease, from early to advanced disease, to learn more about its …
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Tao Wu, MD
… China. He completed neurological and neuroscientific research training at the Department of Clinical … biomarkers for evaluation of disease progression and early diagnosis of Parkinson’s disease, and to understand the …