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Development of a PET Tracer for Imaging of Neuroinflammation in Parkinson’s Disease
… Such a molecular tool could facilitate the early diagnosis of PD. Hypothesis: By characterizing three … Parkinson’s disease: Activation of P2X7R is linked to the early stages of immune-cell activation in the brain and the …
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Quantitative Real-Time Alpha-synuclein Seed Detection by SeRAS®
… of Parkinson’s patients. They can thus enable a reliable diagnosis even at very early disease stages. In order to monitor disease … disease from other synuclein-related disorders even at early disease stages. Next Steps for Development: We will …
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Michael J. Fox on the Importance of the Patient's Voice
June 5, 2015
… 400 Summit on Wednesday. After going public with his diagnosis, Michael saw a chance to put the spotlight on Parkinson's research. “I saw the foundation as an opportunity for me as … As the Foundation has grown, it's brought more voices into the conversation as well. Today, Parkinson’s …
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News in Context: Parkinson’s Biomarker May Be Only Skin Deep
January 10, 2014
… Research has found more alpha-synuclein in the skin of PD … improve diagnostic accuracy. Even in the best of hands, the diagnosis of Parkinson’s disease (PD) may be inaccurate … Second, an accurate and sensitive biomarker could promote early diagnosis. If, for example, we had an effective …
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Identification and Quantification of Parkinson’s Disease Progression Using Digital Measures from a Wrist-worn Wearable Device - a Retrospective Study
… aspects of Parkinson’s disease (PD) care, practice and research. Earlier PD diagnoses may yield better treatment … that digital measures can accurately categorize subjects into known groups of healthy, prodromal PD and severity of … dataset consists of 341 enrolled subjects with varying PD diagnosis and healthy controls and includes sensor data for …
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Detection of Alpha-synuclein Aggregates in Tear Fluid of Patients with Parkinson’s Disease
… detect Parkinson’s disease related protein changes, making diagnosis easier and more patient-friendly. Hypothesis: Can … ensure the test produces consistent results across three research labs and analyze the data to prepare for … then aim to integrate this non-invasive diagnostic method into routine clinical practice and clinical trials. …