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Working Together to End Parkinson’s Forever
… Thank you for joining us. By being a part of our community, you’re contributing to our shared mission to find a cure for Parkinson’s … webpage — created especially for you — to learn more about how we support the Parkinson’s community, stay updated on …
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Using AZP2006 (Ezeprogind) to Stabilize Progranulin – A Novel Therapeutic Strategy for GBA1-linked Parkinson’s Disease
… and changes. They are usually secreted or transported to the lysosome. Its deficiency and inflammation leads to a … for lysosomes. AZP2006 is able to strongly bind the complex PGRN/PSAP (prosaposin) in lysosome and its … for a PD/GBA1 development. In addition, AZP2006 has shown an excellent safety profile, the PK is well known, then …
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How Strategic De-Risking is Fueling Parkinson’s Treatment Development
April 16, 2026
… disease (PD) is a high-stakes endeavor that can be costly, complex and often uncertain. But a growing number of … suggest that de-risking this process may be the key to moving promising therapies forward. By pairing targeted … of cellular proteins and pathways that may contribute to how PD develops and progresses. One of the most advanced …
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Our Mission to Cure Parkinson’s Disease
… The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an … improved therapies for those living with Parkinson's today. How Do We Get to Cures? The Michael J. Fox Foundation (MJFF) … as a critical catalyst in both the patient and the research communities. See More We are risk-takers and problem-solvers …
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Dr. Rachel Dolhun to TIME: "We Need the Patient Experience to Inform Us"
June 2, 2017
… In 1959, Margaret Bourke-White -- the first female photojournalist accredited to cover World War II combat zones -- courageously detailed her experience being … new ways to track and communicate about the symptoms...We need the patient experience to inform us so much, and that's …
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Now Is the Time to Pass the National Plan to End Parkinson’s Disease
April 24, 2024
… The National Plan to End Parkinson’s Act (H.R.2365/S.1064) is the first-ever … treat, and ultimately prevent and cure Parkinson's. Now under consideration in the U.S. Senate, the bill passed … staging framework for the disease — there is no better time to focus our efforts on accelerating science to better …