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Generation of Induced Pluripotent Stem Cells with Indigenous Ancestry to Promote Inclusion of North America’s First Peoples in Parkinson’s Disease Research
… people with Parkinson’s disease (PD) are largely underrepresented in research studies, and biological material from these populations is rarely available to research groups and biobanks. Therefore, to ensure that … will make these cells available to the global PD research community. Impact on Diagnosis/Treatment of Parkinson’s …
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Epigenetic Regulation of the alpha-synuclein Gene as a Biomarker of Susceptibility to PD
… does not account for all phenomena in the clinical expressivity of the disease. For example, in the Contursi … onset age. This observation raises the suspicion that factors other than genetic determinants based on inherited DNA … Contursi kindred and assess the correlation between this outcome measure and age at symptom onset. If a correlation is …
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Parkinson's Organizations Applaud Efforts to Bring More Drugs to Market
March 24, 2014
… PAN and other Parkinson’s organizations applaud efforts to develop new Parkinson’s disease (PD) drugs, but call for … pipeline. All 37 were developed by either U.S.-based companies or foreign companies conducting clinical trials in … disease.” Read more of the PD organizations' statement. Visit the PhRMA site to read the full report. Maggie Kuhl …
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Working with Us
… Learn what it's like to receive funding from the Foundation and partner on our … in Parkinson's research and development. Register for upcoming webinars or watch previous sessions on demand. Learn More Application …
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LEAPS Collaboration to Create First Genetic Map of Parkinson's Disease
June 9, 2004
… announced that the first award under its Linked Efforts to Accelerate Parkinson’s Solutions (LEAPS) program will aim … significantly accelerate the field by quickly providing a comprehensive source of information to the community. What’s … more information about the company and its technologies, visit www.perlegen.com . …
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Multi-tracer positron emission tomography (PET) functional imaging as a tool to assess the relevance of rodent LRRK2 models to the human neurochemical phenotype associated with LRRK2 mutations related Parkinsonism
… Objective/Rationale : Transgenic pre-clinical models are instrumental to investigate mutation-induced abnormalities at the … pre-clinical models to provide a set of observables common to transgenic pre-clinical models and humans. … A. Jon Stoessl, CM/MD/FRCPC/FCAHS …