Andrew B. Singleton, PhD
Chief Laboratory of Neurogenetics at National Institute on Aging / National Institutes of Health
Location: Bethesda, Maryland, United States
Dr Singleton received his B.Sc. from the University of Sunderland, UK and his Ph.D. from the University of Newcastle upon Tyne, UK. Dr Singletonís research initially focused on genetic determinants of dementia, in particular Alzheimerís disease and dementia with Lewy bodies. His postdoctoral studies were spent at the Mayo Clinic in Jacksonville Florida. Dr Singleton moved to the National Institute on Aging at NIH Bethesda, MD in 2001 and became a principal investigator leading the Molecular Genetics Unit in 2002. In 2007 Dr Singleton became a tenured senior investigator at the National Institute on Aging, in 2008 he became the Chief of the Laboratory of Neurogenetics, and in 2016 he was named an NIH Distinguished Investigator.
Dr. Singleton has published more than 500 articles on a wide variety of topics. His laboratory comprises ~50 staff, including five principal investigators and 3 group leaders. His laboratory works on the genetic basis of neurological disorders including Parkinson's disease, Alzheimerís disease, dystonia, ataxia, dementia with Lewy bodies, and amyotrophic lateral sclerosis. The goal of this research is to identify genetic variability that causes or contributes to disease and to use this knowledge to understand the molecular processes underlying disease.
Dr. Singleton currently serves on the scientific advisory board of the Michael J. Fox Foundation and the Lewy Body Dementia Association; he is a member of the editorial boards of Neurodegenerative Diseases, Neurogenetics, Movement Disorders, Brain (Associate Editor, Genetics), Lancet Neurology, the Journal of Parkinsonís Disease, NPJ Parkinsonís Disease, the Journal of Huntingtonís Disease, and Annals of Neurology. Dr. Singleton was awarded the Boehringer Mannheim Research Award in 2005, the NIH Directorís Award in 2008 and again in 2016, and the Annemarie Opprecht Award for Parkinsonís disease research in 2008. In 2012 Dr. Singleton became the first person to win the Jay van Andel Award for Outstanding Achievement in Parkinsonís Disease Research. In 2017 Dr. Singleton was awarded the American Academy of Neurology Movement Disorders Award for lifetime achievement in research and an Honorary Doctorate from his alma mater, the University of Sunderland.