The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.
Search or browse funded studies
Previously funded studies appear chronologically, with the most recent appearing first.
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Rapid Response Innovation Awards, 2013Enteric Glial Cells as a New Source of Biomarkers for PD
Objective/Rationale:
The neural network of the gut called the enteric nervous system (ENS) is affected by the pathological process in PD. One of the relevant features of the ENS is its accessibility... -
Rapid Response Innovation Awards, 2013Protease-Activated Receptor-2 Expression in Parkinson’s Disease
Objective/Rationale:
Inflammation in the brain (neuroinflammation) is an ongoing process in Parkinson's disease and contributes to cell death. Anti-inflammatory compounds are... -
Rapid Response Innovation Awards, 2013The Influence of Bacterial Amyloid on Alpha-synuclein Misfolding in a Pre-clinical Model
Objective/Rationale:
In Parkinson’s disease (PD), in nerve cells in the brain and in the intestine, alpha-synuclein proteins are misformed with abnormal folds and develop small toxic... -
MJFF Research Grant, 2013LRRK2 PET Tracer Development
Promising Outcomes of Original Grant:
With our initial grant from MJFF, we focused on designing and synthesizing chemical matter with physico-chemical properties such that it could travel into the... -
Target Validation, 2013Effects of IL-10 on Neurodegeneration in Mutant Alpha-Synuclein Transgenic Models
Objective/Rationale:
One of the hallmark pathologies in the brains of patients with Parkinson’s disease (PD) is an inflammatory response. We will test whether the cytokine interleukin-10... -
MJFF Research Grant, 2013Development of G2019S Selective LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
Objective/Rationale:
The LRRK2 kinase has been implicated as a potential therapeutic target for the treatment of Parkinson’s disease (PD). The goal of this project is to make experimental...
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Our funding programs support basic, translational and clinical research from academia and industry.