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Funded Studies

The Foundation supports research across basic, translational and clinical science to speed breakthroughs that can lead to the creation of new treatments and a better quality of life for people with Parkinson's disease.

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Previously funded studies appear chronologically, with the most recent appearing first.

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  • Summer 2022 RFP: The Edmond J. Safra Movement Disorders Research Career Development Award, 2022
    Tracking Eye Movements and Pupil Responses as a Diagnostic and Prognostic Biomarker in Parkinsonian Disorders

    Study Rationale: We do not currently have accurate tests to diagnose Parkinson’s disease (PD) and the conditions which mimic it (atypical parkinsonism) at a very early stage. Similarly, we do not have...

  • Research Resources, 2022
    Neural Network Imaging Analysis in Parkinson’s Disease Associated with Parkin Mutation

    Study Rationale: Clinical imaging biomarkers are desperately needed to provide a non-invasive means of assessing therapeutic efficacy in clinical trials for Parkinson’s disease (PD). Recent studies...

  • Research Grant, 2024
    Qualitative Evaluation of Draft Questionnaires for Patient-reported Outcome Measures of Non-motor Symptoms in Early-stage Parkinson's Disease

    Study Rationale: This project seeks to address an unmet need for fit-for-purpose, clinical outcome assessments for early-stage Parkinson’s disease (PD) to be used in clinical trials to capture the...

  • Circuits & Cellular Targets for PD’s Symptoms, 2025
    Role of B2*-Nicotinic Receptors in Parkinson’s Disease Related Circuits and Symptoms

    Study Rationale: One pathological hallmark of Parkinson’s disease (PD) is the degeneration of dopamine neurons innervating the striatum. Dopamine loss is associated with several adaptive changes in...

  • MJFF Research Grant, 2009
    Clinicogenetic Studies of LRRK2 G2019S in Tunisia

    Objective/Rationale:
    Parkinson’s disease (PD) is a prevalent, heterogeneous disorder with a complex, multifactorial etiology. In Tunisia, North Africa, the burden of genetically-defined LRRK2 G2019S...

  • Rapid Response Innovation Awards, 2009
    The Role of Casein Kinase 2 in the Modulation of Dopamine Signaling in Parkinson's Disease

    Objective/Rationale:
    Parkinson’s disease is caused by a selective loss of cells in the brain that produce the neurotransmitter dopamine. The major treatment for PD is Levodopa (L-Dopa) which gets...

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