Doris Du Wang, MD, PhD
Assistant Professor, Department of Neurological Surgery at University of California, San Francisco
Location: San Francisco, CA
United States
Dr. Wang’s research goal is to understand the neural mechanisms that underlie human motor control, study the pathophysiology when these circuits are disrupted in movement disorders, and restore diseased circuits to normal states using neuromodulation. She is a neurosurgeon-scientist specializing in deep brain stimulation surgery (DBS) for patients with movement disorders. Her laboratory records cortical and basal ganglia field potentials directly from the brain of patients with movement disorders in both the intraoperative and ambulatory settings using chronic brain implants. These techniques permit study of cortical-basal ganglia network activities with unparalleled spatiotemporal resolution. Importantly, they translate knowledge gained from human neurophysiological studies directly into therapy, where they develop closed-loop neuromodulation paradigms to treat gait disorders in patients with Parkinson’s disease.
Dr. Wang’s clinical research aim is to advance surgical care for movement disorder patients. This includes studies to improve targeting for DBS and comparison of surgical techniques to clinical outcomes.