3176 - 3200 of 9140 Results
Title
Year
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OPENTitle: Identification of Candidate Parkinson Disease Genes by Integrating Genome-Wide Association Study, Expression, and Epigenetic Data SetsJournal Name: JAMA NeurologyPublisher: American Medical Association (AMA)Vol: 78Issue #: 4Start Page: 464End Page: 464Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1001/jamaneurol.2020.5257Best OA location URL: https://jamanetwork.com/journals/jamaneurology/articlepdf/2775977/jamaneurology_kia_2021_oi_200099_1617209045.71518.pdfCitation Count: 205
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OPENTitle: Falls Risk in Relation to Activity Exposure in High-Risk Older AdultsJournal Name: The Journals of Gerontology: Series APublisher: Oxford University Press (OUP)Vol: 75Issue #: 6Start Page: 1198End Page: 1205Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1093/gerona/glaa007Best OA location URL: https://academic.oup.com/biomedgerontology/article-pdf/75/6/1198/33283332/glaa007.pdfCitation Count: 86
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OPENTitle: Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanismsJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 121Issue #: 6Start Page: 705End Page: 719Publication Date:Open Access(OA) Status: OPENLicense: cc-by-ncDOI - Digital Object Identifier: 10.1007/s00401-011-0806-2Best OA location URL: https://link.springer.com/content/pdf/10.1007/s00401-011-0806-2.pdfCitation Count: 65
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OPENTitle: Striatal Overexpression of ΔJunD Resets L-DOPA-Induced Dyskinesia in a Primate Model of Parkinson DiseaseJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 66Issue #: 6Start Page: 554End Page: 561Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2009.04.005Best OA location URL: http://doi.org/10.1016/j.biopsych.2009.04.005Citation Count: 97
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OPENTitle: Spread of aggregates after olfactory bulb injection of α-synuclein fibrils is associated with early neuronal loss and is reduced long termJournal Name: Acta NeuropathologicaPublisher: Springer Science and Business Media LLCVol: 135Issue #: 1Start Page: 65End Page: 83Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s00401-017-1792-9Best OA location URL: https://link.springer.com/content/pdf/10.1007%2Fs00401-017-1792-9.pdfCitation Count: 226
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RESTRICTEDTitle: Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer’s diseaseJournal Name: BiomarkersPublisher: Informa UK LimitedVol: 14Issue #: 7Start Page: 493End Page: 501Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.3109/13547500903108423Best OA location URL: http://doi.org/10.3109/13547500903108423Citation Count: 110
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OPENTitle: Spatiotemporal Pattern of Striatal ERK1/2 Phosphorylation in a Rat Model of L-DOPA–Induced Dyskinesia and the Role of Dopamine D1 ReceptorsJournal Name: Biological PsychiatryPublisher: Elsevier BVVol: 62Issue #: 7Start Page: 800End Page: 810Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.biopsych.2006.11.032Best OA location URL: http://doi.org/10.1016/j.biopsych.2006.11.032Citation Count: 271
- Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)2010OPENTitle: Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 20Issue #: 17Start Page: 5175End Page: 5178Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2010.07.007Citation Count: 29
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OPENTitle: Efficient estimation of nonparametric genetic risk function with censored dataJournal Name: BiometrikaPublisher: Oxford University Press (OUP)Vol: 102Issue #: 3Start Page: 515End Page: 532Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/biomet/asv030Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4581539Citation Count: 7
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4). Part II: Challenges in hit-to-leadJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 3Start Page: 962End Page: 966Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.11.104Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3787871Citation Count: 58
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OPENTitle: Synthesis and SAR of a novel positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGluR4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 19Issue #: 17Start Page: 4967End Page: 4970Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2009.07.072Best OA location URL: http://doi.org/10.1016/j.bmcl.2009.07.072Citation Count: 38
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OPENTitle: Identifying blood-brain-barrier selective single-chain antibody fragmentsJournal Name: Biotechnology JournalPublisher: WileyVol: 9Issue #: 5Start Page: 664End Page: 674Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/biot.201300550Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4073886Citation Count: 23
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OPENTitle: Conformational heterogeneity of the Roc domains in C. tepidum Roc–COR and implications for human LRRK2 Parkinson mutationsJournal Name: Bioscience ReportsPublisher: Portland Press Ltd.Vol: 35Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1042/bsr20150128Best OA location URL: https://portlandpress.com/bioscirep/article-pdf/35/5/e00254/477473/bsr035e254.pdfCitation Count: 27
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OPENTitle: Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samplesJournal Name: Biotechnology ProgressPublisher: WileyVol: 29Issue #: 2Start Page: 463End Page: 471Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/btpr.1698Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3618510Citation Count: 24
- Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulator2011OPENTitle: Synthesis and SAR of a novel metabotropic glutamate receptor 4 (mGlu4) antagonist: Unexpected ‘molecular switch’ from a closely related mGlu4 positive allosteric modulatorJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 21Issue #: 23Start Page: 6955End Page: 6959Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2011.09.131Citation Count: 18
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OPENTitle: Normalization and expression changes in predefined sets of proteins using 2D gel electrophoresis: A proteomic study of L-DOPA induced dyskinesia in an animal model of Parkinson's disease using DIGEJournal Name: BMC BioinformaticsPublisher: Springer Science and Business Media LLCVol: 7Issue #: 1Start Page: 475End Page: 475Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/1471-2105-7-475Best OA location URL: https://bmcbioinformatics.biomedcentral.com/counter/pdf/10.1186/1471-2105-7-475Citation Count: 38
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OPENTitle: Positive allosteric modulators of the metabotropic glutamate receptor subtype 4 (mGluR4): Part I. Discovery of pyrazolo[3,4-d]pyrimidines as novel mGluR4 positive allosteric modulatorsJournal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 18Issue #: 20Start Page: 5626End Page: 5630Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2008.08.087Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3182458Citation Count: 59
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OPENTitle: Toxic Oligomeric Alpha-Synuclein Variants Present in Human Parkinson’s Disease Brains Are Differentially Generated in Mammalian Cell ModelsJournal Name: BiomoleculesPublisher: MDPI AGVol: 5Issue #: 3Start Page: 1634End Page: 1651Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3390/biom5031634Best OA location URL: http://hdl.handle.net/2286/R.I.43313Citation Count: 40
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OPENTitle: Discovery and characterization of a novel series of N-phenylsulfonyl-1H-pyrrole picolinamides as positive allosteric modulators of the metabotropic glutamate receptor 4 (mGlu4)Journal Name: Bioorganic & Medicinal Chemistry LettersPublisher: Elsevier BVVol: 26Issue #: 13Start Page: 2984End Page: 2987Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.bmcl.2016.05.029Best OA location URL: http://doi.org/10.1016/j.bmcl.2016.05.029Citation Count: 5
- Progression of motor and nonmotor features of Parkinson's disease and their response to treatment2012RESTRICTEDTitle: Progression of motor and nonmotor features of Parkinson's disease and their response to treatmentJournal Name: British Journal of Clinical PharmacologyPublisher: WileyVol: 74Issue #: 2Start Page: 267End Page: 283Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/j.1365-2125.2012.04192.xCitation Count: 186
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OPENTitle: GATA transcription factors directly regulate the Parkinson's disease-linked gene α-synucleinJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 105Issue #: 31Start Page: 10907End Page: 10912Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0802437105Best OA location URL: https://www.pnas.org/content/pnas/105/31/10907.full.pdfCitation Count: 268
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RESTRICTEDTitle: Murine models of acute neuronopathic Gaucher diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: National Academy of SciencesVol: 104Issue #: 44Start Page: 17483End Page: 17488Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1073/pnas.0708086104Best OA location URL: http://doi.org/10.1073/pnas.0708086104Citation Count: 197
- Disease progress and response to treatment as predictors of survival, disability, cognitive impairment and depression in Parkinson's disease2012RESTRICTEDTitle: Disease progress and response to treatment as predictors of survival, disability, cognitive impairment and depression in Parkinson's diseaseJournal Name: British Journal of Clinical PharmacologyPublisher: WileyVol: 74Issue #: 2Start Page: 284End Page: 295Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1111/j.1365-2125.2012.04208.xCitation Count: 46
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OPENTitle: Validation of nigrostriatal positron emission tomography measures: Critical limitsJournal Name: Annals of NeurologyPublisher: WileyVol: 73Issue #: 3Start Page: 390End Page: 396Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/ana.23798Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3631302Citation Count: 89
- Neuron‐to‐neuron transmission of α‐synuclein fibrils through axonal transport2012RESTRICTEDTitle: Neuron‐to‐neuron transmission of α‐synuclein fibrils through axonal transportJournal Name: Annals of NeurologyPublisher: WileyVol: 72Issue #: 4Start Page: 517End Page: 524Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/ana.23747Citation Count: 363