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  • 2021 AAPM&R Annual Assembly Abstracts
    2021
    Summary Details
    RESTRICTED
    Title: 2021 AAPM&R Annual Assembly Abstracts
    Author(s):
    Journal Name: PM&R
    Publisher: Wiley
    Vol: 13
    Issue #: S1
    Start Page: S1
    End Page: S229
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/pmrj.12735
    Citation Count: 29
  • Does MDS‐UPDRS Provide Greater Sensitivity to Mild Disease than UPDRS in De Novo Parkinson's Disease?
    2021
    Summary Details
    OPEN
    Title: Does MDS‐UPDRS Provide Greater Sensitivity to Mild Disease than UPDRS in De Novo Parkinson's Disease?
    Author(s): Michelle Hyczy de Siqueira Tosin, Glenn T. Stebbins, Cynthia L. Comella, Charity G. Patterson, Deborah A. Hall, the SPARX Study Group
    Journal Name: Movement Disorders Clinical Practice
    Publisher: Wiley
    Vol: 8
    Issue #: 7
    Start Page: 1092
    End Page: 1099
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mdc3.13329
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mdc3.13329
    Citation Count: 15
  • Leucine rich repeat kinase 2 (LRRK2) peptide modulators: Recent advances and future directions
    2021
    Summary Details
    RESTRICTED
    Title: Leucine rich repeat kinase 2 (LRRK2) peptide modulators: Recent advances and future directions
    Author(s): Leah G. Helton, Hardy J. Rideout, Friedrich W. Herberg, Eileen J. Kennedy
    Journal Name: Peptide Science
    Publisher: Wiley
    Vol: 114
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/pep2.24251
    Citation Count: 0
  • Alzheimer's Disease Alters Oligodendrocytic Glycolytic and Ketolytic Gene Expression
    2021
    Summary Details
    RESTRICTED
    Title: Alzheimer's Disease Alters Oligodendrocytic Glycolytic and Ketolytic Gene Expression
    Author(s): Erin Saito, Justin Miller, Oscar Harari, Carlos Cruchaga, Kathie A. Mihindukulasuriya, John S. K. Kauwe, Benjamin T. Bikman
    Journal Name: The FASEB Journal
    Publisher: Wiley
    Vol: 35
    Issue #: S1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1096/fasebj.2021.35.s1.02461
    Citation Count: 2
  • Thyroarytenoid Muscle Gene Expression in a Rat Model of Early‐Onset Parkinson's Disease
    2021
    Summary Details
    OPEN
    Title: Thyroarytenoid Muscle Gene Expression in a Rat Model of Early‐Onset Parkinson's Disease
    Author(s): Sarah Lechner, Heidi Kletzien, Stephen C. Gammie, Cynthia A. Kelm‐Nelson
    Journal Name: The Laryngoscope
    Publisher: Wiley
    Vol: 131
    Issue #: 12
    Start Page: E2874
    End Page: E2879
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/lary.29661
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8595495
    Citation Count: 16
  • Focused Workshops
    2021
    Summary Details
    OPEN
    Title: Focused Workshops
    Author(s):
    Journal Name: European Journal of Neurology
    Publisher: Wiley
    Vol: 28
    Issue #: S1
    Start Page: 23
    End Page: 43
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/ene.14970
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ene.14970
    Citation Count: 0
  • Patient and caregiver characteristics associated with caregiver burden in Parkinson’s disease: a palliative care approach
    2019
    Summary Details
    OPEN
    Title: Patient and caregiver characteristics associated with caregiver burden in Parkinson’s disease: a palliative care approach
    Author(s): Zachary A. Macchi, Claire E. Koljack, Janis M. Miyasaki, Maya Katz, Nick Galifianakis, Lindsay P. Prizer, Stefan Sillau, Benzi M. Kluger
    Journal Name: Annals of Palliative Medicine
    Publisher: AME Publishing Company
    Vol: 9
    Issue #: S1
    Start Page: S24
    End Page: S33
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.21037/apm.2019.10.01
    Best OA location URL: https://apm.amegroups.com/article/viewFile/31642/26522
    Citation Count: 161
  • The recent failure of the PROMESA clinical trial for multiple system atrophy raises the question—are polyphenols a viable therapeutic option against proteinopathies?
    2020
    Summary Details
    OPEN
    Title: The recent failure of the PROMESA clinical trial for multiple system atrophy raises the question—are polyphenols a viable therapeutic option against proteinopathies?
    Author(s): Gal Bitan
    Journal Name: Annals of Translational Medicine
    Publisher: AME Publishing Company
    Vol: 8
    Issue #: 11
    Start Page: 719
    End Page: 719
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.21037/atm.2020.01.117
    Best OA location URL: https://atm.amegroups.com/article/viewFile/35635/pdf
    Citation Count: 11
  • Investigating lymphocyte populations in patients with Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: Investigating lymphocyte populations in patients with Parkinson’s disease
    Author(s): Nicolas Dzamko
    Journal Name: Annals of Translational Medicine
    Publisher: AME Publishing Company
    Vol: 8
    Issue #: 6
    Start Page: 276
    End Page: 276
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.21037/atm.2020.02.29
    Best OA location URL: https://atm.amegroups.com/article/viewFile/37712/pdf
    Citation Count: 3
  • Organoid Cultures as Preclinical Models of Non–Small Cell Lung Cancer
    2019
    Summary Details
    RESTRICTED
    Title: Organoid Cultures as Preclinical Models of Non–Small Cell Lung Cancer
    Author(s): Ruoshi Shi, Nikolina Radulovich, Christine Ng, Ni Liu, Hirotsugu Notsuda, Michael Cabanero, Sebastião N. Martins-Filho, Vibha Raghavan, Quan Li, Arvind Singh Mer, Joshua C. Rosen, Ming Li, Yu-Hui Wang, Laura Tamblyn, Nhu‐An Pham, Benjamin Haibe‐Kains, Geoffrey Liu, Nadeem Moghal, Ming‐Sound Tsao
    Journal Name: Clinical Cancer Research
    Publisher: American Association for Cancer Research (AACR)
    Vol: 26
    Issue #: 5
    Start Page: 1162
    End Page: 1174
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1158/1078-0432.ccr-19-1376
    Citation Count: 320
  • Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
    2020
    Summary Details
    OPEN
    Title: Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
    Author(s): Mathieu Bourdenx, Aurélien Nioche, Sandra Doveró, Marie-Laure Arotçarena, Sandrine Camus, Grégory Porras, Marie-Laure Thiolat, N. P. Rougier, Alice Prigent, P. Aubert, Sylvain Bohic, Christophe Sandt, Florent Laferrière, Évelyne Doudnikoff, Niels Kruse, Brit Mollenhauer, Salvatore Novello, Michele Morari, Thierry Lesté-Lasserre, Inés Trigo‐Damas, Michel Goillandeau, Céline Perier, Cristina Estrada, Nuria García‐Carrillo, Ariadna Recasens, Nishant N. Vaikath, Omar M. A. El‐Agnaf, María Trinidad Herrero, Pascal Derkinderen, Miquel Vila, José Á. Obeso, Benjamin Dehay, Erwan Bézard
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 6
    Issue #: 20
    Start Page: eaaz9165
    End Page: eaaz9165
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/sciadv.aaz9165
    Best OA location URL: https://advances.sciencemag.org/content/advances/6/20/eaaz9165.full.pdf
    Citation Count: 59
  • Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
    2020
    Summary Details
    OPEN
    Title: Integrated proteomics reveals brain-based cerebrospinal fluid biomarkers in asymptomatic and symptomatic Alzheimer’s disease
    Author(s): Lenora Higginbotham, Lingyan Ping, Eric B. Dammer, Duc M. Duong, Maotian Zhou, Marla Gearing, Cheyenne Hurst, Jonathan D. Glass, Stewart A. Factor, Erik C. B. Johnson, Ihab Hajjar, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
    Journal Name: Science Advances
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 6
    Issue #: 43
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1126/sciadv.aaz9360
    Best OA location URL: https://advances.sciencemag.org/content/advances/6/43/eaaz9360.full.pdf
    Citation Count: 383
  • Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death
    2020
    Summary Details
    OPEN
    Title: Activation of the Akt1-CREB pathway promotes RNF146 expression to inhibit PARP1-mediated neuronal death
    Author(s): Hyojung Kim, Jisoo Park, Hojin Kang, Seung Pil Yun, Yun‐Song Lee, Yun‐Il Lee, Yunjong Lee
    Journal Name: Science Signaling
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 13
    Issue #: 663
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scisignal.aax7119
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7909008
    Citation Count: 44
  • APOE genotype regulates pathology and disease progression in synucleinopathy
    2020
    Summary Details
    OPEN
    Title: APOE genotype regulates pathology and disease progression in synucleinopathy
    Author(s): Albert A. Davis, Casey E. Inman, Zachary M. Wargel, Umber Dube, Brittany M. Freeberg, Alexander Galluppi, Jessica N. Haines, Dhruva D. Dhavale, Rebecca L. Miller, Fahim A. Choudhury, Patrick M. Sullivan, Carlos Cruchaga, Joel S. Perlmutter, Jason D. Ulrich, Bruno A. Benítez, Paul T. Kotzbauer, David M. Holtzman
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 529
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aay3069
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7289511
    Citation Count: 176
  • Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor
    2020
    Summary Details
    OPEN
    Title: Chronic embedded cortico-thalamic closed-loop deep brain stimulation for the treatment of essential tremor
    Author(s): Enrico Opri, Stephanie Cernera, Rene Molina, Robert S. Eisinger, Jackson Cagle, Leonardo Almeida, Timothy Denison, Michael S. Okun, Kelly D. Foote, Aysegul Gunduz
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 572
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aay7680
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8182660
    Citation Count: 153
  • LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
    2020
    Summary Details
    RESTRICTED
    Title: LRRK2 inhibitors induce reversible changes in nonhuman primate lungs without measurable pulmonary deficits
    Author(s): Marco A. S. Baptista, Kalpana Merchant, Ted Barrett, Sakshi Bhargava, Dianne K. Bryce, J. Michael Ellis, Anthony A. Estrada, Matthew Fell, Brian Fiske, Reina N. Fuji, Paul Galatsis, Anastasia G. Henry, Sue Hill, Warren D. Hirst, Christopher Houle, Matthew Kennedy, Xingrong Liu, Matthew L. Maddess, Carrie G. Markgraf, Hong Mei, William A. Meier, Elie Needle, Stephen Ploch, Christopher M. Royer, Karin Rudolph, Alok Sharma, Antonia F. Stepan, Stefanus J. Steyn, Craig Trost, Zhizhang Yin, Hongshi Yu, Xiang Wang, Todd Sherer
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 540
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aav0820
    Citation Count: 127
  • Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion
    2020
    Summary Details
    OPEN
    Title: Amyloid-like oligomerization of AIMP2 contributes to α-synuclein interaction and Lewy-like inclusion
    Author(s): Sangwoo Ham, Seung Pil Yun, Hyojung Kim, Donghoon Kim, Bo Am Seo, Heejeong Kim, Jeong‐Yong Shin, Mohammad Aasif Dar, Gum Hwa Lee, Yun Il Lee, Yun Il Lee, Doyeun Kim, Sung‐Hoon Kim, Hee-Seok Kweon, Joo‐Ho Shin, Han Seok Ko, Yunjong Lee, Yunjong Lee
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 569
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aax0091
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/8082540
    Citation Count: 28
  • A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease
    2020
    Summary Details
    OPEN
    Title: A patient-based model of RNA mis-splicing uncovers treatment targets in Parkinson’s disease
    Author(s): Ibrahim Boussaad, Carolin D. Obermaier, Zoé Hanss, Dheeraj Reddy Bobbili, Silvia Bolognin, Enrico Glaab, Katarzyna Wicher, Nicole Weisschuh, Laura De Conti, Caroline May, Florian Giesert, Dajana Großmann, Annika Lambert, Susanne Kirchen, Maria Biryukov, Lena F. Burbulla, François Massart, Jill Bohler, Gérald Cruciani, Benjamin Schmid, Annerose Kurz-Drexler, Patrick May, Stefano Duga, Christine Klein, Jens C. Schwamborn, Katrin Marcus, Dirk Woitalla, Daniela M. Vogt Weisenhorn, Wolfgang Wurst, Marco Baralle, Dimitri Krainc, Thomas Gasser, Bernd Wissinger, Rejko Krüger
    Journal Name: Science Translational Medicine
    Publisher: American Association for the Advancement of Science (AAAS)
    Vol: 12
    Issue #: 560
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1126/scitranslmed.aau3960
    Best OA location URL: http://orbilu.uni.lu/handle/10993/44767
    Citation Count: 65
  • Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates
    2020
    Summary Details
    OPEN
    Title: Selective Fluorogenic β-Glucocerebrosidase Substrates for Convenient Analysis of Enzyme Activity in Cell and Tissue Homogenates
    Author(s): Matthew C. Deen, Cameron Proceviat, Xiaoyang Shan, Liang Wu, David L. Shen, G.J. Davies, David J. Vocadlo
    Journal Name: ACS Chemical Biology
    Publisher: American Chemical Society (ACS)
    Vol: 15
    Issue #: 4
    Start Page: 824
    End Page: 829
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschembio.9b01044
    Citation Count: 12
  • Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
    2020
    Summary Details
    OPEN
    Title: Conopeptide-Functionalized Nanoparticles Selectively Antagonize Extrasynaptic N-Methyl-d-aspartate Receptors and Protect Hippocampal Neurons from Excitotoxicity In Vitro
    Author(s): Pierluigi Valente, Darya Kiryushko, Silvio Sacchetti, Pedro Machado, Claire M. Cobley, Vincenzo Mangini, Alexandra E. Porter, Joachim P. Spatz, Roland A. Fleck, Fabio Benfenati, Roberto Fiammengo
    Journal Name: ACS Nano
    Publisher: American Chemical Society (ACS)
    Vol: 14
    Issue #: 6
    Start Page: 6866
    End Page: 6877
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acsnano.0c00866
    Best OA location URL: https://ndownloader.figstatic.com/files/22969427
    Citation Count: 15
  • A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels
    2020
    Summary Details
    OPEN
    Title: A Single Amino Acid Determines the Selectivity and Efficacy of Selective Negative Allosteric Modulators of CaV1.3 L-Type Calcium Channels
    Author(s): Garry Cooper, Soosung Kang, Tamara Perez‐Rosello, Jaime N. Guzmán, Daniel J. Galtieri, Zhong Xie, Jyothisri Kondapalli, Jack Mordell, Richard B. Silverman, D. James Surmeier
    Journal Name: ACS Chemical Biology
    Publisher: American Chemical Society (ACS)
    Vol: 15
    Issue #: 9
    Start Page: 2539
    End Page: 2550
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acschembio.0c00577
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7502546
    Citation Count: 17
  • Virus Bioresistor (VBR) for Detection of Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute
    2020
    Summary Details
    OPEN
    Title: Virus Bioresistor (VBR) for Detection of Bladder Cancer Marker DJ-1 in Urine at 10 pM in One Minute
    Author(s): Apurva Bhasin, Emily C. Sanders, Joshua Ziegler, Jeffrey S. Briggs, Nicholas P. Drago, Aisha Attar, Alicia M. Santos, Marie Y. True, Alana F. Ogata, Debora V. Yoon, Sudipta Majumdar, Andrew Wheat, Shae V. Patterson, Gregory A. Weiss, Reginald M. Penner
    Journal Name: Analytical Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 92
    Issue #: 9
    Start Page: 6654
    End Page: 6666
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1021/acs.analchem.0c00534
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7266010
    Citation Count: 30
  • Choosing a Parkinson Disease Treatment
    2020
    Summary Details
    OPEN
    Title: Choosing a Parkinson Disease Treatment
    Author(s): Melissa J. Armstrong, Michael S. Okun
    Journal Name: JAMA
    Publisher: American Medical Association (AMA)
    Vol: 323
    Issue #: 14
    Start Page: 1420
    End Page: 1420
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/jama.2020.1224
    Best OA location URL: https://jamanetwork.com/journals/jama/articlepdf/2764458/jama_armstrong_2020_pg_200005.pdf
    Citation Count: 37
  • Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils
    2020
    Summary Details
    OPEN
    Title: Intramolecular Povarov Reactions for the Synthesis of Chromenopyridine Fused 2-Pyridone Polyheterocycles Binding to α-Synuclein and Amyloid-β Fibrils
    Author(s): Dan E. Adolfsson, Mohit Tyagi, Pardeep Singh, Adrian Deuschmann, Jörgen Ådén, Anna L. Gharibyan, Sanduni Wasana Jayaweera, Anders E. G. Lindgren, Anders Olofsson, Fredrik Almqvist
    Journal Name: The Journal of Organic Chemistry
    Publisher: American Chemical Society (ACS)
    Vol: 85
    Issue #: 21
    Start Page: 14174
    End Page: 14189
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1021/acs.joc.0c01699
    Best OA location URL: https://pubs.acs.org/doi/pdf/10.1021/acs.joc.0c01699
    Citation Count: 23
  • Palliative Care for Persons Living With Parkinson Disease
    2020
    Summary Details
    OPEN
    Title: Palliative Care for Persons Living With Parkinson Disease
    Author(s): Leonard L. Sokol, Benzi M. Kluger
    Journal Name: JAMA
    Publisher: American Medical Association (AMA)
    Vol: 324
    Issue #: 15
    Start Page: 1579
    End Page: 1579
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/jama.2020.18333
    Best OA location URL: https://jamanetwork.com/journals/jama/articlepdf/2771904/jama_sokol_2020_pg_200052_1602876114.33828.pdf
    Citation Count: 8
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