5301 - 5350 of 8808 Results
Title
Year
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OPENTitle: MHC-I expression renders catecholaminergic neurons susceptible to T-cell-mediated degenerationJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 5Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/ncomms4633Best OA location URL: https://www.nature.com/articles/ncomms4633.pdfCitation Count: 282
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OPENTitle: Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stressJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 102Issue #: 14Start Page: 5215End Page: 5220Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0501282102Best OA location URL: http://doi.org/10.1073/pnas.0501282102Citation Count: 686
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OPENTitle: Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinationsJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 20Issue #: 9Start Page: 1009End Page: 1014Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.06.018Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4143433Citation Count: 46
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OPENTitle: The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during agingJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 101Issue #: 26Start Page: 9843End Page: 9848Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.0403495101Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/470762Citation Count: 473
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OPENTitle: Toll like receptor 4 mediates cell death in a mouse MPTP model of Parkinson diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/srep01393Best OA location URL: https://www.nature.com/articles/srep01393.pdfCitation Count: 150
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OPENTitle: Central and systemic IL-1 exacerbates neurodegeneration and motor symptoms in a model of Parkinson's diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 131Issue #: 7Start Page: 1880End Page: 1894Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/awn101Best OA location URL: https://academic.oup.com/brain/article-pdf/131/7/1880/1093630/awn101.pdfCitation Count: 328
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OPENTitle: Neurologist care in Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 77Issue #: 9Start Page: 851End Page: 857Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e31822c9123Best OA location URL: https://n.neurology.org/content/neurology/77/9/851.full.pdfCitation Count: 265
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RESTRICTEDTitle: PINK1 p.Leu347Pro mutations in Malays: Prevalence and illustrative casesJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 79Issue #:Start Page: 34End Page: 39Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2020.08.015Citation Count: 21
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OPENTitle: CAG repeat expansion in Huntington disease determines age at onset in a fully dominant fashionJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 78Issue #: 10Start Page: 690End Page: 695Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e318249f683Best OA location URL: https://hdl.handle.net/2108/99911Citation Count: 346
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OPENTitle: Increased Expression of α-Synuclein Reduces Neurotransmitter Release by Inhibiting Synaptic Vesicle Reclustering after EndocytosisJournal Name: NeuronPublisher: Elsevier BVVol: 65Issue #: 1Start Page: 66End Page: 79Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuron.2009.12.023Best OA location URL: http://www.cell.com/article/S0896627309010411/pdfCitation Count: 972
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OPENTitle: Subthalamic nucleus stimulation reverses mediofrontal influence over decision thresholdJournal Name: Nature NeurosciencePublisher: Springer Science and Business Media LLCVol: 14Issue #: 11Start Page: 1462End Page: 1467Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/nn.2925Citation Count: 658
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OPENTitle: Directed Differentiation of Dopaminergic Neuronal Subtypes from Human Embryonic Stem CellsJournal Name: STEM CELLSPublisher: Oxford University Press (OUP)Vol: 23Issue #: 6Start Page: 781End Page: 790Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1634/stemcells.2004-0365Best OA location URL: https://academic.oup.com/stmcls/article-pdf/23/6/781/40721656/stmcls_23_6_781.pdfCitation Count: 488
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OPENTitle: Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette SyndromeJournal Name: NeuronPublisher: Elsevier BVVol: 94Issue #: 6Start Page: 1101End Page: 1111.e7Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neuron.2017.06.010Best OA location URL: http://www.cell.com/article/S0896627317305081/pdfCitation Count: 162
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OPENTitle: Differential Neural Activation Patterns in Patients with Parkinson's Disease and Freezing of Gait in Response to Concurrent Cognitive and Motor LoadJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 8Issue #: 1Start Page: e52602End Page: e52602Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0052602Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0052602&type=printableCitation Count: 117
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OPENTitle: Alzheimer brain-derived tau oligomers propagate pathology from endogenous tauJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 2Issue #: 1Start Page: 700End Page: 700Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-saDOI - Digital Object Identifier: 10.1038/srep00700Best OA location URL: https://www.nature.com/articles/srep00700.pdfCitation Count: 485
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OPENTitle: Relative vascular permeability and vascularity across different regions of the rat nasal mucosa: implications for nasal physiology and drug deliveryJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep31732Best OA location URL: https://www.nature.com/articles/srep31732.pdfCitation Count: 52
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OPENTitle: Gastric dysregulation induced by microinjection of 6-OHDA in the substantia nigra pars compacta of rats is determined by alterations in the brain-gut axisJournal Name: American Journal of Physiology-Gastrointestinal and Liver PhysiologyPublisher: American Physiological SocietyVol: 307Issue #: 10Start Page: G1013End Page: G1023Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1152/ajpgi.00258.2014Best OA location URL: http://doi.org/10.1152/ajpgi.00258.2014Citation Count: 47
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OPENTitle: Selective loss of glucocerebrosidase activity in sporadic Parkinson’s disease and dementia with Lewy bodiesJournal Name: Molecular NeurodegenerationPublisher: Springer Science and Business Media LLCVol: 10Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s13024-015-0010-2Best OA location URL: https://molecularneurodegeneration.biomedcentral.com/counter/pdf/10.1186/s13024-015-0010-2Citation Count: 139
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OPENTitle: Nuclear receptor Nurr1 agonists enhance its dual functions and improve behavioral deficits in an animal model of Parkinson’s diseaseJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 112Issue #: 28Start Page: 8756End Page: 8761Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1509742112Best OA location URL: https://www.pnas.org/content/pnas/112/28/8756.full.pdfCitation Count: 184
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OPENTitle: Unaltered Striatal Dopamine Release Levels in Young Parkin Knockout, Pink1 Knockout, DJ-1 Knockout and LRRK2 R1441G Transgenic MiceJournal Name: PLoS ONEPublisher: Public Library of Science (PLoS)Vol: 9Issue #: 4Start Page: e94826End Page: e94826Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0094826Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0094826&type=printableCitation Count: 35
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OPENTitle: Zinc inhibition of rat NR1/NR2AN‐methyl‐d‐aspartate receptorsJournal Name: The Journal of PhysiologyPublisher: WileyVol: 586Issue #: 3Start Page: 763End Page: 778Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1113/jphysiol.2007.143941Best OA location URL: http://doi.org/10.1113/jphysiol.2007.143941Citation Count: 63
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RESTRICTEDTitle: Distinct metabolomic signature in cerebrospinal fluid in early parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 32Issue #: 10Start Page: 1401End Page: 1408Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.27132Best OA location URL: http://orbilu.uni.lu/handle/10993/32300Citation Count: 107
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OPENTitle: Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegansJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34477Best OA location URL: https://www.nature.com/articles/srep34477.pdfCitation Count: 428
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OPENTitle: Multi-objective particle swarm optimization for postoperative deep brain stimulation targeting of subthalamic nucleus pathwaysJournal Name: Journal of Neural EngineeringPublisher: IOP PublishingVol: 15Issue #: 6Start Page: 066020End Page: 066020Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1088/1741-2552/aae12fCitation Count: 37
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OPENTitle: Modeling and optimizing deep brain stimulation to enhance gait in Parkinson’s disease: personalized treatment with neurophysiological insightsJournal Name: npj Parkinson's DiseasePublisher: Springer Science and Business Media LLCVol: 11Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/s41531-025-00990-5Best OA location URL: https://www.nature.com/articles/s41531-025-00990-5.pdfCitation Count: 2
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RESTRICTEDTitle: Ser129 phosphorylation of endogenous α-synuclein induced by overexpression of polo-like kinases 2 and 3 in nigral dopamine neurons is not detrimental to their survival and functionJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 78Issue #:Start Page: 100End Page: 114Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2015.03.008Best OA location URL: https://doaj.org/article/e6cfc888a029486e90bd0c862951a4b1Citation Count: 27
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OPENTitle: Increased iron-deposition in lateral-ventral substantia nigra pars compacta: A promising neuroimaging marker for Parkinson's diseaseJournal Name: NeuroImage: ClinicalPublisher: Elsevier BVVol: 28Issue #:Start Page: 102391End Page: 102391Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-ndDOI - Digital Object Identifier: 10.1016/j.nicl.2020.102391Best OA location URL: https://doi.org/10.1016/j.nicl.2020.102391Citation Count: 35
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OPENTitle: Comparative analysis of methods to reduce activation signature gene expression in PBMCsJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41598-023-49611-2Best OA location URL: https://www.nature.com/articles/s41598-023-49611-2.pdfCitation Count: 6
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OPENTitle: Risk variants of the α-synuclein locus and REM sleep behavior disorder in Parkinson’s disease: a genetic association studyJournal Name: BMC NeurologyPublisher: Springer Science and Business Media LLCVol: 18Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1186/s12883-018-1023-6Best OA location URL: https://bmcneurol.biomedcentral.com/track/pdf/10.1186/s12883-018-1023-6Citation Count: 17
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OPENTitle: Exploring variability in basal ganglia connectivity with functional MRI in healthy agingJournal Name: Brain Imaging and BehaviorPublisher: Springer Science and Business Media LLCVol: 12Issue #: 6Start Page: 1822End Page: 1827Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1007/s11682-018-9824-1Best OA location URL: https://link.springer.com/content/pdf/10.1007%2Fs11682-018-9824-1.pdfCitation Count: 24
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OPENTitle: Open science takes on Parkinson’s diseaseJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 10Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.66546Best OA location URL: https://doi.org/10.7554/elife.66546Citation Count: 7
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OPENTitle: Remote smartphone monitoring of Parkinson’s disease and individual response to therapyJournal Name: Nature BiotechnologyPublisher: Springer Science and Business Media LLCVol: 40Issue #: 4Start Page: 480End Page: 487Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41587-021-00974-9Best OA location URL: http://hdl.handle.net/2066/252104Citation Count: 117
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OPENTitle: MAPT haplotype–stratified GWAS reveals differential association for AD risk variantsJournal Name: Alzheimer's & DementiaPublisher: WileyVol: 16Issue #: 7Start Page: 983End Page: 1002Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1002/alz.12099Best OA location URL: https://doi.org/10.1002/alz.12099Citation Count: 37
- Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s disease2025OPENTitle: Haploinsufficiency of ITSN1 is associated with a substantial increased risk of Parkinson’s diseaseJournal Name: Cell ReportsPublisher: Elsevier BVVol: 44Issue #: 3Start Page: 115355End Page: 115355Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.celrep.2025.115355Best OA location URL: https://www.cell.com/action/showPdf?pii=S2211124725001263Citation Count: 2
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OPENTitle: African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1Journal Name: Nature Structural & Molecular BiologyPublisher: Springer Science and Business Media LLCVol: 31Issue #: 12Start Page: 1955End Page: 1963Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41594-024-01423-2Best OA location URL: https://www.nature.com/articles/s41594-024-01423-2.pdfCitation Count: 5
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OPENTitle: Crowdsourcing digital health measures to predict Parkinson’s disease severity: the Parkinson’s Disease Digital Biomarker DREAM ChallengeJournal Name: npj Digital MedicinePublisher: Springer Science and Business Media LLCVol: 4Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41746-021-00414-7Best OA location URL: https://www.nature.com/articles/s41746-021-00414-7.pdfCitation Count: 50
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OPENTitle: Use of Glycolysis‐Enhancing Drugs and Risk of Parkinson's DiseaseJournal Name: Movement DisordersPublisher: WileyVol: 37Issue #: 11Start Page: 2210End Page: 2216Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1002/mds.29184Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/mds.29184Citation Count: 23
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OPENTitle: From a deep learning model back to the brain—Identifying regional predictors and their relation to agingJournal Name: Human Brain MappingPublisher: WileyVol: 41Issue #: 12Start Page: 3235End Page: 3252Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc, cc-by-ncDOI - Digital Object Identifier: 10.1002/hbm.25011Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.25011Citation Count: 87
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OPENTitle: Dopamine neuron activity encodes the length of upcoming contralateral movement sequencesJournal Name: Current BiologyPublisher: Elsevier BVVol: 34Issue #: 5Start Page: 1034End Page: 1047.e4Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.cub.2024.01.067Best OA location URL: http://www.cell.com/article/S0960982224001040/pdfCitation Count: 6
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OPENTitle: Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learningJournal Name: Cell SystemsPublisher: Elsevier BVVol: 15Issue #: 5Start Page: 475End Page: 482.e6Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.cels.2024.04.006Best OA location URL: http://www.cell.com/article/S2405471224001212/pdfCitation Count: 9
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OPENTitle: Group patient visits for Parkinson diseaseJournal Name: NeurologyPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 76Issue #: 18Start Page: 1542End Page: 1547Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182194badBest OA location URL: https://n.neurology.org/content/neurology/76/18/1542.full.pdfCitation Count: 22
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RESTRICTEDTitle: VAMP2 chaperones α-synuclein in synaptic vesicle co-condensatesJournal Name: Nature Cell BiologyPublisher: Springer Science and Business Media LLCVol: 26Issue #: 8Start Page: 1287End Page: 1295Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1038/s41556-024-01456-1Best OA location URL: https://pmc.ncbi.nlm.nih.gov/articles/PMC11786254/pdf/nihms-2046227.pdfCitation Count: 23
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OPENTitle: The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damageJournal Name: Nature Cell BiologyPublisher: Springer Science and Business Media LLCVol: 27Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41556-025-01653-6Best OA location URL: https://www.nature.com/articles/s41556-025-01653-6.pdfCitation Count: 1
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OPENTitle: Deficiency of the frontotemporal dementia gene GRN results in gangliosidosisJournal Name: Nature CommunicationsPublisher: Springer Science and Business Media LLCVol: 13Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41467-022-33500-9Best OA location URL: https://www.nature.com/articles/s41467-022-33500-9.pdfCitation Count: 73
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OPENTitle: New insights into the genetic etiology of Alzheimer’s disease and related dementiasJournal Name: Nature GeneticsPublisher: Springer Science and Business Media LLCVol: 54Issue #: 4Start Page: 412End Page: 436Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41588-022-01024-zBest OA location URL: https://www.nature.com/articles/s41588-022-01024-z.pdfCitation Count: 1694
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OPENTitle: EndoMAP.v1 charts the structural landscape of human early endosome complexesJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 643Issue #: 8070Start Page: 252End Page: 261Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1038/s41586-025-09059-yBest OA location URL: https://www.nature.com/articles/s41586-025-09059-y.pdfCitation Count: 0
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OPENTitle: In situ architecture of the lipid transport protein VPS13C at ER–lysosome membrane contactsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 119Issue #: 29Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-by, cc-byDOI - Digital Object Identifier: 10.1073/pnas.2203769119Best OA location URL: https://doi.org/10.1073/pnas.2203769119Citation Count: 62
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OPENTitle: Association of vitamin K with cognitive decline and neuropathology in community‐dwelling older personsJournal Name: Alzheimer's & Dementia: Translational Research & Clinical InterventionsPublisher: WileyVol: 8Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1002/trc2.12255Best OA location URL: https://doi.org/10.1002/trc2.12255Citation Count: 42
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OPENTitle: A cerebrospinal fluid synaptic protein biomarker for prediction of cognitive resilience versus decline in Alzheimer’s diseaseJournal Name: Nature MedicinePublisher: Springer Science and Business Media LLCVol: 31Issue #: 5Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by-nc-nd, cc-by-nc-ndDOI - Digital Object Identifier: 10.1038/s41591-025-03565-2Best OA location URL: https://www.nature.com/articles/s41591-025-03565-2.pdfCitation Count: 19
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OPENTitle: Structure of LRRK2 in Parkinson’s disease and model for microtubule interactionJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 588Issue #: 7837Start Page: 344End Page: 349Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/s41586-020-2673-2Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/7726071Citation Count: 203