6701 - 6750 of 8436 Results
Title
Year
- Sixty‐hertz stimulation improves bradykinesia and amplifies subthalamic low‐frequency oscillations2016RESTRICTEDTitle: Sixty‐hertz stimulation improves bradykinesia and amplifies subthalamic low‐frequency oscillationsJournal Name: Movement DisordersPublisher: WileyVol: 32Issue #: 1Start Page: 80End Page: 88Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26837Citation Count: 63
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OPENTitle: Assessing Visuospatial Skills in Parkinson's: Comparison of Neuropsychological Assessment Battery Visual Discrimination to the Judgment of Line OrientationJournal Name: Archives of Clinical NeuropsychologyPublisher: Oxford University Press (OUP)Vol: 32Issue #: 1Start Page: 123End Page: 127Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/arclin/acw102Best OA location URL: https://academic.oup.com/acn/article-pdf/32/1/123/9951631/acw102.pdfCitation Count: 4
- Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons2016OPENTitle: Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neuronsJournal Name: Proceedings of the National Academy of SciencesPublisher: Proceedings of the National Academy of SciencesVol: 113Issue #: 47Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1073/pnas.1608784113Best OA location URL: https://www.pnas.org/content/pnas/113/47/E7564.full.pdfCitation Count: 53
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OPENTitle: Low-dose Lithium Treatment for Agitation and Psychosis in Alzheimer Disease and Frontotemporal DementiaJournal Name: Alzheimer Disease & Associated DisordersPublisher: Ovid Technologies (Wolters Kluwer Health)Vol: 31Issue #: 1Start Page: 73End Page: 75Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1097/wad.0000000000000161Best OA location URL: https://europepmc.org/articles/pmc5322244?pdf=renderCitation Count: 66
- Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanism2016RESTRICTEDTitle: Heterozygous PINK1 p.G411S increases risk of Parkinson’s disease via a dominant-negative mechanismJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 140Issue #: 1Start Page: 98End Page: 117Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-ncDOI - Digital Object Identifier: 10.1093/brain/aww261Best OA location URL: https://academic.oup.com/brain/article-pdf/140/1/98/24174204/aww261.pdfCitation Count: 116
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OPENTitle: Progression of Regional Microstructural Degeneration in Parkinson’s Disease: A Multicenter Diffusion Tensor Imaging StudyJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 11Issue #: 10Start Page: e0165540End Page: e0165540Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0165540Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0165540&type=printableCitation Count: 88
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OPENTitle: Intake of antioxidant vitamins and risk of Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 12Start Page: 1909End Page: 1914Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26819Best OA location URL: https://europepmc.org/articles/pmc5154924?pdf=renderCitation Count: 102
- c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson’s Disease2016RESTRICTEDTitle: c-Abl Inhibitors Enable Insights into the Pathophysiology and Neuroprotection in Parkinson’s DiseaseJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 8Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2016.00254Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2016.00254/pdfCitation Count: 38
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OPENTitle: TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tauJournal Name: eLifePublisher: eLife Sciences Publications, LtdVol: 5Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.7554/elife.19809Best OA location URL: https://doi.org/10.7554/elife.19809Citation Count: 117
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OPENTitle: A harmonized segmentation protocol for hippocampal and parahippocampal subregions: Why do we need one and what are the key goals?Journal Name: HippocampusPublisher: WileyVol: 27Issue #: 1Start Page: 3End Page: 11Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/hipo.22671Best OA location URL: https://discovery.ucl.ac.uk/1528722/1/Wisse_et_al-2016-Hippocampus.pdfCitation Count: 158
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OPENTitle: CSF Biomarkers and Its Associations with 18F-AV133 Cerebral VMAT2 Binding in Parkinson’s Disease—A Preliminary ReportJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 11Issue #: 10Start Page: e0164762End Page: e0164762Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0164762Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0164762&type=printableCitation Count: 17
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OPENTitle: White matter microstructural characteristics in newly diagnosed Parkinson’s disease: An unbiased whole-brain studyJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep35601Best OA location URL: https://www.nature.com/articles/srep35601.pdfCitation Count: 42
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RESTRICTEDTitle: Is Axonal Degeneration a Key Early Event in Parkinson’s Disease?Journal Name: Journal of Parkinson's DiseasePublisher: IOS PressVol: 6Issue #: 4Start Page: 703End Page: 707Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.3233/jpd-160881Best OA location URL: http://darchive.mblwhoilibrary.org/bitstreams/2010ffba-e9af-51c2-a5bd-d7afa7449372/downloadCitation Count: 39
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OPENTitle: T2-Imaging Changes in the Nigrosome-1 Relate to Clinical Measures of Parkinson’s DiseaseJournal Name: Frontiers in NeurologyPublisher: Frontiers Media SAVol: 7Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fneur.2016.00174Best OA location URL: https://www.frontiersin.org/articles/10.3389/fneur.2016.00174/pdfCitation Count: 10
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RESTRICTEDTitle: The Effects of Physical Activity in Parkinson’s Disease: A ReviewJournal Name: Journal of Parkinson's DiseasePublisher: IOS PressVol: 6Issue #: 4Start Page: 685End Page: 698Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-ncDOI - Digital Object Identifier: 10.3233/jpd-160790Best OA location URL: https://europepmc.org/articles/pmc5088404?pdf=renderCitation Count: 138
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OPENTitle: Clinical and demographic characteristics related to onset site and spread of cervical dystoniaJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 12Start Page: 1874End Page: 1882Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26817Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5154862Citation Count: 43
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OPENTitle: Dexmedetomidine for refractory adrenergic crisis in familial dysautonomiaJournal Name: Clinical Autonomic ResearchPublisher: Springer Science and Business Media LLCVol: 27Issue #: 1Start Page: 7End Page: 15Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s10286-016-0383-5Best OA location URL: https://europepmc.org/articles/pmc5292083?pdf=renderCitation Count: 13
- Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity2016OPENTitle: Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severityJournal Name: Neurobiology of AgingPublisher: Elsevier BVVol: 50Issue #:Start Page: 39End Page: 46Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2016.10.006Citation Count: 11
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OPENTitle: RNF213 Is Associated with Intracranial Aneurysms in the French-Canadian PopulationJournal Name: The American Journal of Human GeneticsPublisher: Elsevier BVVol: 99Issue #: 5Start Page: 1072End Page: 1085Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.ajhg.2016.09.001Best OA location URL: http://www.cell.com/article/S0002929716303792/pdfCitation Count: 60
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OPENTitle: Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progressionJournal Name: PROTEOMICSPublisher: WileyVol: 16Issue #: 23Start Page: 3042End Page: 3053Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/pmic.201600057Best OA location URL: https://europepmc.org/articles/pmc5462625?pdf=renderCitation Count: 82
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OPENTitle: Dual Tasking for the Differentiation between Depression and Mild Cognitive ImpairmentJournal Name: Frontiers in Aging NeurosciencePublisher: Frontiers Media SAVol: 8Issue #:Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.3389/fnagi.2016.00235Best OA location URL: https://www.frontiersin.org/articles/10.3389/fnagi.2016.00235/pdfCitation Count: 18
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OPENTitle: Digitized Spiral Drawing: A Possible Biomarker for Early Parkinson’s DiseaseJournal Name: PLOS ONEPublisher: Public Library of Science (PLoS)Vol: 11Issue #: 10Start Page: e0162799End Page: e0162799Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1371/journal.pone.0162799Best OA location URL: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0162799&type=printableCitation Count: 99
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OPENTitle: mTOR independent regulation of macroautophagy by Leucine Rich Repeat Kinase 2 via Beclin-1Journal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep35106Best OA location URL: https://doi.org/10.1038/srep35106Citation Count: 73
- Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s disease2016RESTRICTEDTitle: Preclinical and clinical assessment of inhaled levodopa for OFF episodes in Parkinson’s diseaseJournal Name: Science Translational MedicinePublisher: American Association for the Advancement of Science (AAAS)Vol: 8Issue #: 360Start Page:End Page:Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1126/scitranslmed.aad8858Citation Count: 67
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OPENTitle: Additional rare variant analysis in Parkinson’s disease cases with and without known pathogenic mutations: evidence for oligogenic inheritanceJournal Name: Human Molecular GeneticsPublisher: Oxford University Press (OUP)Vol:Issue #:Start Page: ddw348End Page: ddw348Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1093/hmg/ddw348Best OA location URL: https://academic.oup.com/hmg/article-pdf/25/24/5483/10408585/ddw348.pdfCitation Count: 50
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OPENTitle: Cognitive function in 1736 participants in NINDS Exploratory Trials in PD Long-term Study-1Journal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 33Issue #:Start Page: 127End Page: 133Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.10.005Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6091572Citation Count: 10
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OPENTitle: Machine Learning Interface for Medical Image AnalysisJournal Name: Journal of Digital ImagingPublisher: Springer Science and Business Media LLCVol: 30Issue #: 5Start Page: 615End Page: 621Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1007/s10278-016-9910-0Best OA location URL: https://link.springer.com/content/pdf/10.1007/s10278-016-9910-0.pdfCitation Count: 58
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RESTRICTEDTitle: Neuropsychological impairment in prodromal Parkinson's diseaseJournal Name: Journal of the Neurological SciencesPublisher: Elsevier BVVol: 371Issue #:Start Page: 117End Page: 120Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.jns.2016.10.007Citation Count: 14
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OPENTitle: Human whole genome genotype and transcriptome data for Alzheimer’s and other neurodegenerative diseasesJournal Name: Scientific DataPublisher: Springer Science and Business Media LLCVol: 3Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/sdata.2016.89Best OA location URL: https://www.nature.com/articles/sdata201689.pdfCitation Count: 425
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OPENTitle: Impaired contrast sensitivity is associated with more severe cognitive impairment in Parkinson diseaseJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 34Issue #:Start Page: 15End Page: 19Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.10.006Best OA location URL: https://europepmc.org/articles/pmc5222688?pdf=renderCitation Count: 36
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OPENTitle: N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylaseJournal Name: Neurobiology of DiseasePublisher: Elsevier BVVol: 96Issue #:Start Page: 323End Page: 334Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.nbd.2016.10.001Best OA location URL: https://europepmc.org/articles/pmc5102763?pdf=renderCitation Count: 36
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OPENTitle: Exposure to the Functional Bacterial Amyloid Protein Curli Enhances Alpha-Synuclein Aggregation in Aged Fischer 344 Rats and Caenorhabditis elegansJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34477Best OA location URL: https://www.nature.com/articles/srep34477.pdfCitation Count: 419
- Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degeneration2016OPENTitle: Study of LRRK2 variation in tauopathy: Progressive supranuclear palsy and corticobasal degenerationJournal Name: Movement DisordersPublisher: WileyVol: 32Issue #: 1Start Page: 115End Page: 123Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1002/mds.26815Best OA location URL: https://europepmc.org/articles/pmc5269612?pdf=renderCitation Count: 59
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OPENTitle: Computer keyboard interaction as an indicator of early Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34468Best OA location URL: https://doi.org/10.1038/srep34468Citation Count: 98
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RESTRICTEDTitle: AAV viral vector delivery to the brain by shape-conforming MR-guided infusionsJournal Name: Journal of Controlled ReleasePublisher: Elsevier BVVol: 240Issue #:Start Page: 434End Page: 442Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.jconrel.2016.02.034Citation Count: 36
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RESTRICTEDTitle: Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1648Issue #:Start Page: 603End Page: 616Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by, cc-byDOI - Digital Object Identifier: 10.1016/j.brainres.2016.02.033Best OA location URL: https://doi.org/10.1016/j.brainres.2016.02.033Citation Count: 39
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RESTRICTEDTitle: Gene therapy to target ER stress in brain diseasesJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1648Issue #:Start Page: 561End Page: 570Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.brainres.2016.04.064Citation Count: 31
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RESTRICTEDTitle: Injury to the nervous system: A look into the ERJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1648Issue #:Start Page: 617End Page: 625Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.brainres.2016.04.053Citation Count: 24
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RESTRICTEDTitle: LRRK2 inhibitors and their potential in the treatment of Parkinson’s disease: current perspectivesJournal Name: Clinical Pharmacology: Advances and ApplicationsPublisher: Informa UK LimitedVol: Volume 8Issue #:Start Page: 177End Page: 189Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-by-ncDOI - Digital Object Identifier: 10.2147/cpaa.s102191Best OA location URL: https://www.dovepress.com/getfile.php?fileID=33080Citation Count: 41
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OPENTitle: Perspective: Data sharing for discoveryJournal Name: NaturePublisher: Springer Science and Business Media LLCVol: 538Issue #: 7626Start Page: S4End Page: S4Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1038/538s4aBest OA location URL: https://www.nature.com/articles/538S4a.pdfCitation Count: 6
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RESTRICTEDTitle: The best medicine? The influence of physical activity and inactivity on Parkinson's diseaseJournal Name: Movement DisordersPublisher: WileyVol: 31Issue #: 10Start Page: 1444End Page: 1454Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1002/mds.26728Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9491025Citation Count: 97
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RESTRICTEDTitle: Pharmacologic antagonism of dopamine receptor D3 attenuates neurodegeneration and motor impairment in a mouse model of Parkinson's diseaseJournal Name: NeuropharmacologyPublisher: Elsevier BVVol: 113Issue #:Start Page: 110End Page: 123Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1016/j.neuropharm.2016.09.028Citation Count: 56
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OPENTitle: Cognitive impairment in Parkinson's disease: Association between patient-reported and clinically measured outcomesJournal Name: Parkinsonism & Related DisordersPublisher: Elsevier BVVol: 33Issue #:Start Page: 107End Page: 114Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1016/j.parkreldis.2016.09.025Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5154808Citation Count: 24
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OPENTitle: Integrative transcriptomic meta-analysis of Parkinson’s disease and depression identifies NAMPT as a potential blood biomarker for de novo Parkinson’s diseaseJournal Name: Scientific ReportsPublisher: Springer Science and Business Media LLCVol: 6Issue #: 1Start Page:End Page:Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1038/srep34579Best OA location URL: https://www.nature.com/articles/srep34579.pdfCitation Count: 38
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OPENTitle: PREFACE: Divergent roles of ER stress in neurodegeneration and brain disordersJournal Name: Brain ResearchPublisher: Elsevier BVVol: 1648Issue #:Start Page: 527End Page: 529Publication Date:Open Access(OA) Status: OPENLicense: publisher-specific-oaDOI - Digital Object Identifier: 10.1016/j.brainres.2016.09.014Best OA location URL: http://manuscript.elsevier.com/S0006899316306229/pdf/S0006899316306229.pdfCitation Count: 1
- Reproducibility of locus coeruleus and substantia nigra imaging with neuromelanin sensitive MRI2016RESTRICTEDTitle: Reproducibility of locus coeruleus and substantia nigra imaging with neuromelanin sensitive MRIJournal Name: Magnetic Resonance Materials in Physics, Biology and MedicinePublisher: Springer Science and Business Media LLCVol: 30Issue #: 2Start Page: 121End Page: 125Publication Date:Open Access(OA) Status: RESTRICTEDLicense:DOI - Digital Object Identifier: 10.1007/s10334-016-0590-zCitation Count: 77
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OPENTitle: Ade novocompound targeting α-synuclein improves deficits in models of Parkinson’s diseaseJournal Name: BrainPublisher: Oxford University Press (OUP)Vol: 139Issue #: 12Start Page: 3217End Page: 3236Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1093/brain/aww238Best OA location URL: https://academic.oup.com/brain/article-pdf/139/12/3217/24173157/aww238.pdfCitation Count: 134
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OPENTitle: SWATH-MS proteome profiling data comparison of DJ-1, Parkin, and PINK1 knockout rat striatal mitochondriaJournal Name: Data in BriefPublisher: Elsevier BVVol: 9Issue #:Start Page: 589End Page: 593Publication Date:Open Access(OA) Status: OPENLicense: cc-byDOI - Digital Object Identifier: 10.1016/j.dib.2016.09.031Best OA location URL: https://doi.org/10.1016/j.dib.2016.09.031Citation Count: 12
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RESTRICTEDTitle: Immunomodulators as Therapeutic Agents in Mitigating the Progression of Parkinson’s DiseaseJournal Name: Brain SciencesPublisher: MDPI AGVol: 6Issue #: 4Start Page: 41End Page: 41Publication Date:Open Access(OA) Status: RESTRICTEDLicense: cc-byDOI - Digital Object Identifier: 10.3390/brainsci6040041Best OA location URL: https://www.mdpi.com/2076-3425/6/4/41/pdf?version=1474633139Citation Count: 18
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OPENTitle: Self-Reported Symptoms of Parkinson’s Disease by Sex and Disease DurationJournal Name: Western Journal of Nursing ResearchPublisher: SAGE PublicationsVol: 39Issue #: 11Start Page: 1412End Page: 1428Publication Date:Open Access(OA) Status: OPENLicense:DOI - Digital Object Identifier: 10.1177/0193945916670904Best OA location URL: https://europepmc.org/articles/pmc5505809?pdf=renderCitation Count: 13