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  • Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    2013
    Summary Details
    OPEN
    Title: Bacillus Calmette-Guerin vaccine-mediated neuroprotection is associated with regulatory T-cell induction in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease
    Author(s): Goran Laćan, Hoa Dang, Blake Middleton, Marcus A. Horwitz, Jide Tian, William P. Melega, Daniel L. Kaufman
    Journal Name: Journal of Neuroscience Research
    Publisher: Wiley
    Vol: 91
    Issue #: 10
    Start Page: 1292
    End Page: 1302
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/jnr.23253
    Best OA location URL: http://doi.org/10.1002/jnr.23253
    Citation Count: 58
  • Parkin mediates the degradation‐independent ubiquitination of Hsp70
    2008
    Summary Details
    OPEN
    Title: Parkin mediates the degradation‐independent ubiquitination of Hsp70
    Author(s): Darren J. Moore, Andrew B. West, Dustin Dikeman, Valina L. Dawson, Ted M. Dawson
    Journal Name: Journal of Neurochemistry
    Publisher: Wiley
    Vol: 105
    Issue #: 5
    Start Page: 1806
    End Page: 1819
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1111/j.1471-4159.2008.05261.x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4432938
    Citation Count: 99
  • Impact of belief in neuroprotection on therapeutic intervention in Parkinson's disease
    2010
    Summary Details
    RESTRICTED
    Title: Impact of belief in neuroprotection on therapeutic intervention in Parkinson's disease
    Author(s): Rodger J. Elble, Oksana Suchowersky, Stephanie Shaftman, William J. Weiner, Peng Huang, BARBARA TILLEY, On Behalf of the NINDS NET‐PD Investigators, Rodger J. Elble, Oksana Suchowersky, William J. Weiner, Peng Huang, BARBARA TILLEY, On Behalf of the NINDS NET‐PD Investigators
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 8
    Start Page: 1082
    End Page: 1086
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.22997
    Citation Count: 1
  • FGF20 and Parkinson's disease: No evidence of association or pathogenicity via α‐synuclein expression
    2009
    Summary Details
    OPEN
    Title: FGF20 and Parkinson's disease: No evidence of association or pathogenicity via α‐synuclein expression
    Author(s): Christian Wider, Justus C. Dächsel, Alexandra I. Soto, Michael G. Heckman, Nancy N. Diehl, Mei Yue, Sarah Lincoln, Jan Aasly, Kristoffer Haugarvoll, John Q. Trojanowski, Spiridon Papapetropoulos, Deborah C. Mash, Alex Rajput, Ali H. Rajput, J. Mark Gibson, Timothy Lynch, Dennis W. Dickson, Ryan J. Uitti, Zbigniew K. Wszołek, Matthew J. Farrer, Owen A. Ross
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 24
    Issue #: 3
    Start Page: 455
    End Page: 459
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.22442
    Best OA location URL: http://doi.org/10.1002/mds.22442
    Citation Count: 44
  • Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1
    2017
    Summary Details
    OPEN
    Title: Par3 and aPKC regulate BACE1 endosome-to-TGN trafficking through PACS1
    Author(s): Miao Sun, Huaye Zhang, Miao Sun, Huaye Zhang
    Journal Name: Neurobiology of Aging
    Publisher: Elsevier BV
    Vol: 60
    Issue #:
    Start Page: 129
    End Page: 140
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.neurobiolaging.2017.08.024
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5653456
    Citation Count: 26
  • Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samples
    2013
    Summary Details
    OPEN
    Title: Isolation and characterization of antibody fragments selective for specific protein morphologies from nanogram antigen samples
    Author(s): Srinath Kasturirangan, Tim Reasoner, Philip Schulz, Shanta Boddapati, Sharareh Emadi, Jon Valla, Michael R. Sierks
    Journal Name: Biotechnology Progress
    Publisher: Wiley
    Vol: 29
    Issue #: 2
    Start Page: 463
    End Page: 471
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/btpr.1698
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3618510
    Citation Count: 24
  • Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators
    2018
    Summary Details
    OPEN
    Title: Activation of the mGlu1 metabotropic glutamate receptor has antipsychotic-like effects and is required for efficacy of M4 muscarinic receptor allosteric modulators
    Author(s): Samantha E. Yohn, Daniel J. Foster, Dan P. Covey, Mark S. Moehle, Jordan Galbraith, Pedro M. García-Barrantes, Hyekyung P. Cho, Michael Bubser, Anna L. Blobaum, Max E. Joffe, Joseph F. Cheer, Carrie K. Jones, Craig W. Lindsley, P. Jeffrey Conn
    Journal Name: Molecular Psychiatry
    Publisher: Springer Science and Business Media LLC
    Vol: 25
    Issue #: 11
    Start Page: 2786
    End Page: 2799
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41380-018-0206-2
    Best OA location URL: https://www.nature.com/articles/s41380-018-0206-2.pdf
    Citation Count: 46
  • Stress and the risk of multiple sclerosis
    2011
    Summary Details
    OPEN
    Title: Stress and the risk of multiple sclerosis
    Author(s): Trond Riise, David C. Mohr, Kassandra L. Munger, Janet W. Rich‐Edwards, Ichiro Kawachi, Alberto Ascherio
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 76
    Issue #: 22
    Start Page: 1866
    End Page: 1871
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e31821d74c5
    Best OA location URL: https://n.neurology.org/content/neurology/76/22/1866.full.pdf
    Citation Count: 68
  • Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery
    2009
    Summary Details
    OPEN
    Title: Nicotine is a Selective Pharmacological Chaperone of Acetylcholine Receptor Number and Stoichiometry. Implications for Drug Discovery
    Author(s): Henry A. Lester, Cheng Xiao, Rahul Srinivasan, Cagdas D Son, Julie Miwa, Rigo Pantoja, Matthew R. Banghart, Dennis A Dougherty, Alison M. Goate, Jen C. Wang, Henry A. Lester, Cheng Xiao, Rahul Srinivasan, Cagdas D Son, Julie Miwa, Rigo Pantoja, Matthew R. Banghart, Dennis A Dougherty, Alison M. Goate, Jen C. Wang
    Journal Name: The AAPS Journal
    Publisher: Springer Science and Business Media LLC
    Vol: 11
    Issue #: 1
    Start Page: 167
    End Page: 177
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1208/s12248-009-9090-7
    Best OA location URL: http://doi.org/10.1208/s12248-009-9090-7
    Citation Count: 160
  • Cognitive performance of GBA mutation carriers with early-onset PD
    2012
    Summary Details
    OPEN
    Title: Cognitive performance of GBA mutation carriers with early-onset PD
    Author(s): Roy N. Alcalay, Elise Caccappolo, Helen Mejia‐Santana, Ming Tang, L. Rosado, Martha Orbe Reilly, Dylanis Lopez Ruiz, B. Ross, Miguel Verbitsky, Sergey Kisselev, Elan D. Louis, Cynthia Comella, Amy Colcher, Danna Jennings, Martha Nance, Susan Bressman, William K. Scott, Caroline M. Tanner, Stuart J. Mickel, Howard Andrews, Cheryl Waters, Stanley Fahn, L. Côté, Steven J. Frucht, B. Ford, Michael Rezak, Kevin Novak, Joseph H. Friedman, Ronald F. Pfeiffer, Laura Marsh, Bradley C. Hiner, Andrew Siderowf, Haydeh Payami, Eric Molho, Stewart A. Factor, Ruth Ottman, Lorraine N. Clark, Karen Marder
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 78
    Issue #: 18
    Start Page: 1434
    End Page: 1440
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e318253d54b
    Best OA location URL: https://n.neurology.org/content/neurology/78/18/1434.full.pdf
    Citation Count: 258
  • Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding Activities
    2011
    Summary Details
    OPEN
    Title: Autophosphorylation in the Leucine-Rich Repeat Kinase 2 (LRRK2) GTPase Domain Modifies Kinase and GTP-Binding Activities
    Author(s): Philip J. Webber, Archer D. Smith, Saurabh Sen, Matthew B. Renfrow, James A. Mobley, Andrew B. West
    Journal Name: Journal of Molecular Biology
    Publisher: Elsevier BV
    Vol: 412
    Issue #: 1
    Start Page: 94
    End Page: 110
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jmb.2011.07.033
    Citation Count: 123
  • Calcium channel blocker use and risk of Parkinson's disease
    2010
    Summary Details
    RESTRICTED
    Title: Calcium channel blocker use and risk of Parkinson's disease
    Author(s): Kelly Claire Simon, Xiang Gao, Honglei Chen, Michael A. Schwarzschild, Alberto Ascherio, Xiang Gao, Honglei Chen, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 12
    Start Page: 1818
    End Page: 1822
    Publication Date:
    Open Access(OA) Status: RESTRICTED
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23191
    Citation Count: 42
  • Dysregulation of 14‐3‐3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology
    2017
    Summary Details
    OPEN
    Title: Dysregulation of 14‐3‐3 proteins in neurodegenerative diseases with Lewy body or Alzheimer pathology
    Author(s): Michael B. McFerrin, Xiaofei Chi, Gary Cutter, Talene A. Yacoubian
    Journal Name: Annals of Clinical and Translational Neurology
    Publisher: Wiley
    Vol: 4
    Issue #: 7
    Start Page: 466
    End Page: 477
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc-nd
    DOI - Digital Object Identifier: 10.1002/acn3.421
    Best OA location URL: https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/acn3.421
    Citation Count: 38
  • Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
    2013
    Summary Details
    OPEN
    Title: Pathogenic Parkinson’s disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation
    Author(s): Claudia Manzoni, Adamantios Mamais, Sybille Dihanich, Phillip McGoldrick, Michael J. Devine, Julia Zerle, Eleanna Kara, Jan‐Willem Taanman, Daniel G. Healy, J.F. Martí-Massó, Anthony H.V. Schapira, Hélène Plun‐Favreau, Sharon A. Tooze, John Hardy, Rina Bandopadhyay, Patrick A. Lewis
    Journal Name: Biochemical and Biophysical Research Communications
    Publisher: Elsevier BV
    Vol: 441
    Issue #: 4
    Start Page: 862
    End Page: 866
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.bbrc.2013.10.159
    Best OA location URL: https://doi.org/10.1016/j.bbrc.2013.10.159
    Citation Count: 82
  • Clinical expression of LRRK2 G2019S mutations in the elderly
    2010
    Summary Details
    OPEN
    Title: Clinical expression of LRRK2 G2019S mutations in the elderly
    Author(s): Marta San Luciano, Richard B. Lipton, Cuiling Wang, Mindy J. Katz, Molly E. Zimmerman, Amy E. Sanders, Laurie J. Ozelius, Susan Bressman, Rachel Saunders‐Pullman
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 25
    Issue #: 15
    Start Page: 2571
    End Page: 2576
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23330
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/2978804
    Citation Count: 23
  • Postmortem interval effect on RNA and gene expression in human brain tissue
    2010
    Summary Details
    OPEN
    Title: Postmortem interval effect on RNA and gene expression in human brain tissue
    Author(s): Alex C. Birdsill, Douglas G. Walker, Lih‐Fen Lue, Lucia I. Sue, Thomas G. Beach
    Journal Name: Cell and Tissue Banking
    Publisher: Springer Science and Business Media LLC
    Vol: 12
    Issue #: 4
    Start Page: 311
    End Page: 318
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s10561-010-9210-8
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3343031
    Citation Count: 146
  • Spinal Cord Stimulation Alleviates Motor Deficits in a Primate Model of Parkinson Disease
    2014
    Summary Details
    OPEN
    Title: Spinal Cord Stimulation Alleviates Motor Deficits in a Primate Model of Parkinson Disease
    Author(s): Maxwell Barbosa de Santana, Pär Halje, Hougelle Simplício Gomes Pereira, Ulrike Richter, Marco Aurélio M. Freire, Per Petersson, Rómulo Fuentes, Miguel A. L. Nicolelis
    Journal Name: Neuron
    Publisher: Elsevier BV
    Vol: 84
    Issue #: 4
    Start Page: 716
    End Page: 722
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.neuron.2014.08.061
    Best OA location URL: http://www.cell.com/article/S0896627314008964/pdf
    Citation Count: 111
  • Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study
    2015
    Summary Details
    OPEN
    Title: Eltoprazine counteracts l-DOPA-induced dyskinesias in Parkinson’s disease: a dose-finding study
    Author(s): Per Svenningsson, Carl Rosenblad, Karolina af Edholm Arvidsson, Klas Wictorin, Charlotte Keywood, Bavani Shankar, David Lowe, Anders Björklund, Håkan Widner
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 138
    Issue #: 4
    Start Page: 963
    End Page: 973
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1093/brain/awu409
    Best OA location URL: https://kclpure.kcl.ac.uk/ws/files/148083964/Eltoprazine_counteracts_L_DOPA_induced_SVENNINGSSON_Publishedonline5February2015_GOLD_VoR_CC_BY_NC_.pdf
    Citation Count: 152
  • Molecular markers of early Parkinson's disease based on gene expression in blood
    2007
    Summary Details
    OPEN
    Title: Molecular markers of early Parkinson's disease based on gene expression in blood
    Author(s): Clemens R. Scherzer, Aron C. Eklund, Lee Jae Morse, Zhixiang Liao, Joseph J. Locascio, Daniel Fefer, Michael A. Schwarzschild, Michael G. Schlossmacher, Michael A. Hauser, Jeffery M. Vance, Lewis Sudarsky, David G. Standaert, John H. Growdon, Roderick V. Jensen, Steven R. Gullans
    Journal Name: Proceedings of the National Academy of Sciences
    Publisher: Proceedings of the National Academy of Sciences
    Vol: 104
    Issue #: 3
    Start Page: 955
    End Page: 960
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1073/pnas.0610204104
    Best OA location URL: http://doi.org/10.1073/pnas.0610204104
    Citation Count: 502
  • CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson Diseases
    2008
    Summary Details
    OPEN
    Title: CSF Multianalyte Profile Distinguishes Alzheimer and Parkinson Diseases
    Author(s): Jing Zhang, Izabela Sokal, Elaine R. Peskind, Joseph F. Quinn, Joseph Jankovic, Christopher Kenney, Kathryn A. Chung, Steven P. Millard, John G. Nutt, Thomas J. Montine
    Journal Name: American Journal of Clinical Pathology
    Publisher: Oxford University Press (OUP)
    Vol: 129
    Issue #: 4
    Start Page: 526
    End Page: 529
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1309/w01y0b808emeh12l
    Best OA location URL: https://academic.oup.com/ajcp/article-pdf/129/4/526/24985935/ajcpath129-0526.pdf
    Citation Count: 263
  • Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
    2012
    Summary Details
    OPEN
    Title: Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy
    Author(s): René L. Vidal, Alicia Tamayo Figueroa, Felipe A. Court, Peter Thielen, C Molina, Craig Wirth, Benjamı́n Caballero, Roberta Kiffin, Juan Segura‐Aguilar, Ana María Cuervo, Laurie H. Glimcher, Claudio Hetz
    Journal Name: Human Molecular Genetics
    Publisher: Oxford University Press (OUP)
    Vol: 21
    Issue #: 10
    Start Page: 2245
    End Page: 2262
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/hmg/dds040
    Best OA location URL: https://academic.oup.com/hmg/article-pdf/21/10/2245/17254728/dds040.pdf
    Citation Count: 268
  • Diagnosis and Referral Delay in Women With Parkinson's Disease
    2011
    Summary Details
    OPEN
    Title: Diagnosis and Referral Delay in Women With Parkinson's Disease
    Author(s): Rachel Saunders‐Pullman, Cuiling Wang, Kaili Stanley, Susan Bressman
    Journal Name: Gender Medicine
    Publisher: Elsevier BV
    Vol: 8
    Issue #: 3
    Start Page: 209
    End Page: 217
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.genm.2011.05.002
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3966522
    Citation Count: 64
  • Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease
    2018
    Summary Details
    OPEN
    Title: Metabolomic Profiling of Bile Acids in an Experimental Model of Prodromal Parkinson’s Disease
    Author(s): Stewart F. Graham, Nolwen L. Rey, Zafer Ugur, Ali Yılmaz, Eric Sherman, Michael Maddens, Ray Bahado‐Singh, Katelyn Becker, Emily Schulz, Lindsay Meyerdirk, Jennifer A. Steiner, Jiyan Ma, Patrik Brundin
    Journal Name: Metabolites
    Publisher: MDPI AG
    Vol: 8
    Issue #: 4
    Start Page: 71
    End Page: 71
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.3390/metabo8040071
    Best OA location URL: https://www.mdpi.com/2218-1989/8/4/71/pdf
    Citation Count: 51
  • Obesity, diabetes, and risk of Parkinson's disease
    2011
    Summary Details
    OPEN
    Title: Obesity, diabetes, and risk of Parkinson's disease
    Author(s): Natalia Palacios, Xiang Gao, Marjorie L. McCullough, Eric J. Jacobs, Alpa V. Patel, Tinisha L. Mayo, Michael A. Schwarzschild, Alberto Ascherio
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 26
    Issue #: 12
    Start Page: 2253
    End Page: 2259
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.23855
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/3627531
    Citation Count: 160
  • Treatment of myoclonus-dystonia syndrome with tetrabenazine
    2014
    Summary Details
    OPEN
    Title: Treatment of myoclonus-dystonia syndrome with tetrabenazine
    Author(s): Angelo Y. Luciano, Hyder A. Jinnah, Ronald F. Pfeiffer, Daniel Truong, Martha Nance, Mark S. LeDoux
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 20
    Issue #: 12
    Start Page: 1423
    End Page: 1426
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2014.09.029
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4254189
    Citation Count: 34
  • Adipose and leptomeningeal arteriole endothelial dysfunction induced by β-amyloid peptide: A practical human model to study Alzheimer's disease vasculopathy
    2014
    Summary Details
    OPEN
    Title: Adipose and leptomeningeal arteriole endothelial dysfunction induced by β-amyloid peptide: A practical human model to study Alzheimer's disease vasculopathy
    Author(s): Seth Truran, Daniel Franco, Alex E. Roher, Thomas G. Beach, Camelia Burciu, Geidy E. Serrano, Chera L. Maarouf, Sara Schwab, Jenna Anderson, Joseph Georges, Peter D. Reaven, Raymond Q. Migrino
    Journal Name: Journal of Neuroscience Methods
    Publisher: Elsevier BV
    Vol: 235
    Issue #:
    Start Page: 123
    End Page: 129
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.jneumeth.2014.06.014
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/4175686
    Citation Count: 15
  • Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients
    2013
    Summary Details
    OPEN
    Title: Safety/feasibility of targeting the substantia nigra with AAV2-neurturin in Parkinson patients
    Author(s): Raymond T. Bartus, Tiffany Baumann, João Siffert, Christopher D. Herzog, Ron L. Alterman, Nicholas M. Boulis, Dennis A. Turner, Mark Stacy, Anthony E. Lang, Andrés M. Lozano, C. Warren Olanow
    Journal Name: Neurology
    Publisher: Ovid Technologies (Wolters Kluwer Health)
    Vol: 80
    Issue #: 18
    Start Page: 1698
    End Page: 1701
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1212/wnl.0b013e3182904faa
    Best OA location URL: https://n.neurology.org/content/neurology/80/18/1698.full.pdf
    Citation Count: 197
  • Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson’s Disease and Control Subjects
    2016
    Summary Details
    OPEN
    Title: Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson’s Disease and Control Subjects
    Author(s): Thomas G. Beach, Anne-Gaëlle Corbillé, Franck Letournel, Jeffrey H. Kordower, Thomas Kremer, David G. Muñoz, Anthony J. Intorcia, Joseph G. Hentz, Charles H. Adler, Lucia I. Sue, Jessica E. Walker, Geidy E. Serrano, Pascal Derkinderen
    Journal Name: Journal of Parkinson’s Disease
    Publisher: SAGE Publications
    Vol: 6
    Issue #: 4
    Start Page: 761
    End Page: 770
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.3233/jpd-160888
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5501392
    Citation Count: 88
  • Epidemiology and neuropsychiatric manifestations of Young Onset Parkinson's Disease in the United States
    2012
    Summary Details
    OPEN
    Title: Epidemiology and neuropsychiatric manifestations of Young Onset Parkinson's Disease in the United States
    Author(s): Allison W. Willis, Mario Schootman, Nina Kung, Brad A. Racette
    Journal Name: Parkinsonism & Related Disorders
    Publisher: Elsevier BV
    Vol: 19
    Issue #: 2
    Start Page: 202
    End Page: 206
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1016/j.parkreldis.2012.09.014
    Citation Count: 46
  • Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease
    2018
    Summary Details
    OPEN
    Title: Stool Immune Profiles Evince Gastrointestinal Inflammation in Parkinson's Disease
    Author(s): Madelyn C. Houser, Jianjun Chang, Stewart A. Factor, Eric Molho, Cyrus P. Zabetian, Erin M. Hill‐Burns, Haydeh Payami, Vicki Hertzberg, Malú G. Tansey
    Journal Name: Movement Disorders
    Publisher: Wiley
    Vol: 33
    Issue #: 5
    Start Page: 793
    End Page: 804
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1002/mds.27326
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/5992021
    Citation Count: 162
  • Mechanism of parkin activation by PINK1
    2018
    Summary Details
    OPEN
    Title: Mechanism of parkin activation by PINK1
    Author(s): Christina Gladkova, Sarah Maslen, Mark Skehel, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 559
    Issue #: 7714
    Start Page: 410
    End Page: 414
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/s41586-018-0224-x
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6071873
    Citation Count: 326
  • Structure of PINK1 in complex with its substrate ubiquitin
    2017
    Summary Details
    OPEN
    Title: Structure of PINK1 in complex with its substrate ubiquitin
    Author(s): Alexander F. Schubert, Christina Gladkova, Els Pardon, Jane L. Wagstaff, Stefan M.V. Freund, Jan Steyaert, Sarah Maslen, David Komander
    Journal Name: Nature
    Publisher: Springer Science and Business Media LLC
    Vol: 552
    Issue #: 7683
    Start Page: 51
    End Page: 56
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/nature24645
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6020998
    Citation Count: 157
  • Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
    2009
    Summary Details
    OPEN
    Title: Glucocerebrosidase mutations in clinical and pathologically proven Parkinson's disease
    Author(s): Juliane Neumann, José Brás, Emma Deas, Sean S. O’Sullivan, Laura Parkkinen, Robin Lachmann, Abi Li, Janice L. Holton, Rita Guerreiro, Reema Paudel, Badmavady Segarane, Andrew Singleton, Andrew J. Lees, John Hardy, Henry Houlden, Tamás Révész, Nicholas Wood
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 132
    Issue #: 7
    Start Page: 1783
    End Page: 1794
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/awp044
    Best OA location URL: https://academic.oup.com/brain/article-pdf/132/7/1783/13734818/awp044.pdf
    Citation Count: 668
  • Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
    2008
    Summary Details
    OPEN
    Title: Phenotype, genotype, and worldwide genetic penetrance of LRRK2-associated Parkinson's disease: a case-control study
    Author(s): Daniel G Healy, Mario Falchi, Sean S. O’Sullivan, Vincenzo Bonifati, Alexandra Durr, Susan Bressman, Alexis Brice, Jan Aasly, Cyrus P. Zabetian, Stefano Goldwurm, Joaquim J. Ferreira, Eduardo Tolosa, Denise M. Kay, Christine Klein, David R. Williams, Connie Marras, Anthony E Lang, Zbigniew K. Wszolek, José Berciano, Anthony HV. Schapira, Timothy Lynch, Kailash P. Bhatia, Thomas Gasser, Andrew J. Lees, Nicholas W. Wood
    Journal Name: The Lancet Neurology
    Publisher: Elsevier BV
    Vol: 7
    Issue #: 7
    Start Page: 583
    End Page: 590
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/s1474-4422(08)70117-0
    Best OA location URL: http://www.thelancet.com/article/S1474442208701170/pdf
    Citation Count: 1518
  • Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-PD study
    2014
    Summary Details
    OPEN
    Title: Genetic impact on cognition and brain function in newly diagnosed Parkinson’s disease: ICICLE-PD study
    Author(s): Cristina Nombela, James B. Rowe, Sophie Winder‐Rhodes, Adam Hampshire, Adrian M. Owen, David P. Breen, Gordon W. Duncan, Tien K. Khoo, Alison J. Yarnall, Michael Firbank, Patrick F. Chinnery, Trevor W. Robbins, John T. O’Brien, David J. Brooks, David J. Burn, Roger A. Barker
    Journal Name: Brain
    Publisher: Oxford University Press (OUP)
    Vol: 137
    Issue #: 10
    Start Page: 2743
    End Page: 2758
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1093/brain/awu201
    Best OA location URL: https://academic.oup.com/brain/article-pdf/137/10/2743/11140806/awu201.pdf
    Citation Count: 144
  • Sequential Voluntary Cough and Aspiration or Aspiration Risk in Parkinson’s Disease
    2014
    Summary Details
    OPEN
    Title: Sequential Voluntary Cough and Aspiration or Aspiration Risk in Parkinson’s Disease
    Author(s): Karen Wheeler‐Hegland, Michael S. Okun, Michelle S. Troche
    Journal Name: Lung
    Publisher: Springer Science and Business Media LLC
    Vol: 192
    Issue #: 4
    Start Page: 601
    End Page: 608
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s00408-014-9584-7
    Best OA location URL: http://doi.org/10.1007/s00408-014-9584-7
    Citation Count: 89
  • Vagally mediated effects of brain stem dopamine on gastric tone and phasic contractions of the rat
    2017
    Summary Details
    OPEN
    Title: Vagally mediated effects of brain stem dopamine on gastric tone and phasic contractions of the rat
    Author(s): Laura Anselmi, Luca Toti, Cecilia Bove, R. Alberto Travagli
    Journal Name: American Journal of Physiology-Gastrointestinal and Liver Physiology
    Publisher: American Physiological Society
    Vol: 313
    Issue #: 5
    Start Page: G434
    End Page: G441
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1152/ajpgi.00180.2017
    Best OA location URL: https://www.physiology.org/doi/pdf/10.1152/ajpgi.00180.2017
    Citation Count: 24
  • Patients’ Opinions on Genetic Counseling on the Increased Risk of Parkinson Disease among Gaucher Disease Carriers
    2017
    Summary Details
    OPEN
    Title: Patients’ Opinions on Genetic Counseling on the Increased Risk of Parkinson Disease among Gaucher Disease Carriers
    Author(s): Maureen Mulhern, Louise Bier, Roy N. Alcalay, Manisha Balwani
    Journal Name: Journal of Genetic Counseling
    Publisher: Wiley
    Vol: 27
    Issue #: 3
    Start Page: 675
    End Page: 680
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s10897-017-0161-0
    Citation Count: 20
  • Cerebral blood flow in Alzheimer’s disease
    2012
    Summary Details
    OPEN
    Title: Cerebral blood flow in Alzheimer’s disease
    Author(s): Alex E. Roher, Debbins, Michael Malek‐Ahmadi, Pipe, Maze, Belden, Maarouf, Hunter, Kokjohn, Walker, Kruchowsky, BĚlohlávek, Mary Catherine Beach, Marwan N. Sabbagh, Kewei Chen, Hua Mo, Pradeep Thiyyagura
    Journal Name: Vascular Health and Risk Management
    Publisher: Informa UK Limited
    Vol:
    Issue #:
    Start Page: 599
    End Page: 599
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.2147/vhrm.s34874
    Best OA location URL: https://www.dovepress.com/getfile.php?fileID=14292
    Citation Count: 187
  • USP14 inhibition enhances Parkin-independent mitophagy in iNeurons
    2024
    Summary Details
    OPEN
    Title: USP14 inhibition enhances Parkin-independent mitophagy in iNeurons
    Author(s): Greta Bernardo, Miguel A. Prado, Anna Roshani Dashtmian, Mariavittoria Favaro, Sofia Mauri, Alice Borsetto, Elena Marchesan, João A. Paulo, Steve P. Gygi, Daniel Finley, Elena Ziviani
    Journal Name: Pharmacological Research
    Publisher: Elsevier BV
    Vol: 210
    Issue #:
    Start Page: 107484
    End Page: 107484
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.phrs.2024.107484
    Best OA location URL: https://doi.org/10.1016/j.phrs.2024.107484
    Citation Count: 2
  • Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease
    2018
    Summary Details
    OPEN
    Title: Age- and disease-dependent increase of the mitophagy marker phospho-ubiquitin in normal aging and Lewy body disease
    Author(s): Xu Hou, Fabienne C. Fiesel, Dominika Truban, Monica Castanedes Casey, Wen-Lang Lin, Alexandra I. Soto, Paweł Tacik, Linda Rousseau, Nancy N. Diehl, Michael G. Heckman, Oswaldo Lorenzo‐Betancor, Isidró Ferrer, José Matías Arbelo, John C. Steele, Matthew J. Farrer, Mario Cornejo‐Olivas, Luis Torres, Ignácio F. Mata, Neill R. Graff‐Radford, Zbigniew K. Wszołek, Owen A. Ross, Melissa E. Murray, Dennis W. Dickson, Wolfdieter Springer
    Journal Name: Autophagy
    Publisher: Informa UK Limited
    Vol: 14
    Issue #: 8
    Start Page: 1404
    End Page: 1418
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1080/15548627.2018.1461294
    Best OA location URL: https://www.tandfonline.com/doi/pdf/10.1080/15548627.2018.1461294?needAccess=true
    Citation Count: 121
  • Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
    2010
    Summary Details
    OPEN
    Title: Inhibition of LRRK2 kinase activity leads to dephosphorylation of Ser910/Ser935, disruption of 14-3-3 binding and altered cytoplasmic localization
    Author(s): Nicolas Dzamko, Mária Deák, Fayçal Hentati, Alastair D. Reith, Alan R. Prescott, Dario R. Alessi, R. Jeremy Nichols
    Journal Name: Biochemical Journal
    Publisher: Portland Press Ltd.
    Vol: 430
    Issue #: 3
    Start Page: 405
    End Page: 413
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1042/bj20100784
    Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/405/664434/bj4300405.pdf
    Citation Count: 377
  • Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
    2008
    Summary Details
    OPEN
    Title: Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity
    Author(s): Liyan Qiao, Shusei Hamamichi, Kim A. Caldwell, Guy A. Caldwell, Talene A. Yacoubian, Scott M. Wilson, Zuolei Xie, Lisa D Speake, Rachael Parks, Donna Crabtree, Qiuli Liang, Stephen Crimmins, Lonnie Schneider, Yasuo Uchiyama, Takeshi Iwatsubo, Yi Zhou, Lisheng Peng, Youming Lu, David G. Standaert, Ken C. Walls, John J. Shacka, Kevin A. Roth, Jianhua Zhang
    Journal Name: Molecular Brain
    Publisher: Springer Science and Business Media LLC
    Vol: 1
    Issue #: 1
    Start Page:
    End Page:
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1186/1756-6606-1-17
    Best OA location URL: https://molecularbrain.biomedcentral.com/counter/pdf/10.1186/1756-6606-1-17
    Citation Count: 244
  • Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
    2017
    Summary Details
    OPEN
    Title: Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling
    Author(s): Martin A. Michel, Kirby N. Swatek, Manuela K. Hospenthal, David Komander
    Journal Name: Molecular Cell
    Publisher: Elsevier BV
    Vol: 68
    Issue #: 1
    Start Page: 233
    End Page: 246.e5
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by
    DOI - Digital Object Identifier: 10.1016/j.molcel.2017.08.020
    Best OA location URL: http://www.cell.com/article/S1097276517306172/pdf
    Citation Count: 179
  • Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis
    2012
    Summary Details
    OPEN
    Title: Stress-Induced Phosphorylation and Proteasomal Degradation of Mitofusin 2 Facilitates Mitochondrial Fragmentation and Apoptosis
    Author(s): Guillaume P. Leboucher, Yien Che Tsai, Mei Yang, Kristin C. Shaw, Ming Zhou, Timothy D. Veenstra, Michael H. Glickman, Allan M. Weissman
    Journal Name: Molecular Cell
    Publisher: Elsevier BV
    Vol: 47
    Issue #: 4
    Start Page: 547
    End Page: 557
    Publication Date:
    Open Access(OA) Status: OPEN
    License: publisher-specific-oa
    DOI - Digital Object Identifier: 10.1016/j.molcel.2012.05.041
    Best OA location URL: http://www.cell.com/article/S1097276512004868/pdf
    Citation Count: 310
  • Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s Disease
    2018
    Summary Details
    OPEN
    Title: Amyloid-β Increases Tau by Mediating Sirtuin 3 in Alzheimer’s Disease
    Author(s): Junxiang Yin, Pengcheng Han, Melissa Song, Megan Nielsen, Thomas G. Beach, Geidy E. Serrano, Winnie S. Liang, Richard J. Caselli, Jiong Shi
    Journal Name: Molecular Neurobiology
    Publisher: Springer Science and Business Media LLC
    Vol: 55
    Issue #: 11
    Start Page: 8592
    End Page: 8601
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1007/s12035-018-0977-0
    Best OA location URL: https://www.ncbi.nlm.nih.gov/pmc/articles/6677544
    Citation Count: 70
  • 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    2010
    Summary Details
    OPEN
    Title: 14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
    Author(s): R. Jeremy Nichols, Nicolas Dzamko, Nicholas A. Morrice, David G. Campbell, Mária Deák, Alban Ordureau, Thomas Macartney, Youren Tong, Jie Shen, Alan R. Prescott, Dario R. Alessi
    Journal Name: Biochemical Journal
    Publisher: Portland Press Ltd.
    Vol: 430
    Issue #: 3
    Start Page: 393
    End Page: 404
    Publication Date:
    Open Access(OA) Status: OPEN
    License: cc-by-nc
    DOI - Digital Object Identifier: 10.1042/bj20100483
    Best OA location URL: https://portlandpress.com/biochemj/article-pdf/430/3/393/878058/bj4300393.pdf
    Citation Count: 385
  • Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging Initiative
    2011
    Summary Details
    OPEN
    Title: Treatment With Cholinesterase Inhibitors and Memantine of Patients in the Alzheimer's Disease Neuroimaging Initiative
    Author(s): Lon S. Schneider, Philip S. Insel, Michael W. Weiner
    Journal Name: Archives of Neurology
    Publisher: American Medical Association (AMA)
    Vol: 68
    Issue #: 1
    Start Page: 58
    End Page: 58
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1001/archneurol.2010.343
    Citation Count: 151
  • Heterogeneity of Cholinergic Denervation in Parkinson's Disease without Dementia
    2012
    Summary Details
    OPEN
    Title: Heterogeneity of Cholinergic Denervation in Parkinson's Disease without Dementia
    Author(s): Nicolaas I. Bohnen, Martijn L.T.M. Müller, Vikas Kotagal, Robert A. Koeppe, Michael R. Kilbourn, Sid Gilman, Roger L. Albin, Kirk A. Frey
    Journal Name: Journal of Cerebral Blood Flow & Metabolism
    Publisher: SAGE Publications
    Vol: 32
    Issue #: 8
    Start Page: 1609
    End Page: 1617
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1038/jcbfm.2012.60
    Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1038/jcbfm.2012.60
    Citation Count: 174
  • Metabolic network expression in parkinsonism: Clinical and dopaminergic correlations
    2016
    Summary Details
    OPEN
    Title: Metabolic network expression in parkinsonism: Clinical and dopaminergic correlations
    Author(s): Ji Hyun Ko, Chong Sik Lee, David Eidelberg
    Journal Name: Journal of Cerebral Blood Flow & Metabolism
    Publisher: SAGE Publications
    Vol: 37
    Issue #: 2
    Start Page: 683
    End Page: 693
    Publication Date:
    Open Access(OA) Status: OPEN
    License:
    DOI - Digital Object Identifier: 10.1177/0271678x16637880
    Best OA location URL: https://journals.sagepub.com/doi/pdf/10.1177/0271678X16637880
    Citation Count: 58
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