… The moment in your doctor's office when you get a Parkinson's diagnosis usually comes as a shock. Without much background knowledge of the … everyone, this question is difficult for doctors to answer. However, it can still be helpful to hear an overview of the …

… from brain for evidence of somatic mutations that have led to a change in the number of copies of relevant genes, … in the level of DNA for alpha-synuclein and our other target genes. This change would result from one in five cells … when preventative drugs are available. Anticipated Outcome:           We will provide the first data on whether …

… the enzyme kynurenine 3-monooxygenase (KMO) as a target to develop drugs to treat PD (PD). KMO is expressed in cells … in brain. Project Description: Our laboratory has shown that a pre-clinical model of PD, over-expression of … to the clinic to treat patients with PD. Anticipated Outcome: We expect to determine whether inhibiting KMO is a …

… grant: Investigating signaling pathway dysfunction linked to LRRK2 Promising Outcomes of Original Grant: Our project investigated whether … cell called the mTOR pathway. This pathway helps to control how cells respond to starvation, and has been linked to a …

… Research (MJFF) submitted a petition with 107,000 signatories, urging the United States Environmental Protection … pesticides and other chemicals, they must understand if and how these substances impact disease risk," said Ted … MJFF. "This collective action by thousands of Parkinson's community members helps educate the EPA on paraquat's …

… (PD) is a defining moment in everyone's life. In others, children never knew a parent or grandparent without … her father; PD is just a part of that. Roberts shares his story in our new guide on Talking to Children and Teens about Parkinson's. No matter when or how Parkinson's enters a child's world, there will be …