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Development of Posiphen to Treat Parkinson's Disease
… Posiphen is a small molecule drug that inhibits expression of alpha-synuclein, a protein involved in … We propose studies in a pre-clinical model of PD to test the potential of Posiphen as a treatment of PD. … models have the gastrointestinal manifestations commonly seen in early PD, including constipation and slow …
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Easing Into Retirement with Parkinson’s
October 8, 2025
… Stepping back from the workforce is a milestone event in any life, and Parkinson’s disease (PD) adds an … a care partner and people who work with the Parkinson’s community discuss retirement and Parkinson’s. They share … rather listen on the go, subscribe to the show on iTunes or wherever you get your podcasts. If you enjoyed what you …
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Strength training patients with Parkinson’s Disease for Dysphagia
… as the disease progresses. When foreign material enters into the airway it is called aspiration and can lead to … uses a device that helps the muscles involved in swallow become active with the intent on combating the bradykinetic, … used in breathing. This technique uses an experimental pressure threshold device to accomplish the strength …
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Ask the MD: Telemedicine Tips for People with Hearing, Vision, Speech or Cognitive Changes
August 20, 2020
… During the pandemic, when in-person visits are limited, many people with Parkinson’s are seeing their doctors virtually through telemedicine. While it can be … cues and even lip reading. Use a bigger screen, such as a computer desktop instead of a telephone. Sit behind or next …
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Getting Better Sleep with Parkinson's
… Sleep is essential to brain health, but for many people with Parkinson’s, it doesn’t come easily. Changes in brain chemistry, movement symptoms … risk factors such as RBD to understand how to treat and prevent brain disease. Learn More …
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Discovery of Changes in N-linked Glycans Associated with Parkinson’s Disease
… The objective of this study is to explore the role of glycans (sugars attached to proteins) … limitations. This study will leverage pharmaceutical company Ezose’s novel, high-throughput technology, the … be separated into two categories: 1) sustained changes, where the concentration of 18 glycans increased gradually …