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Studying Structures of LRRK2 to Understand and Slow Parkinson's Disease
… upon the research from a prior grant: Structure Window into LRRK2: Kinase or Pseudokinase? Study Rationale: Mutations … structures with experimental techniques and investigate how LRRK2 functions and changes within the cell by creating … structures lays the foundation for designing therapies targeting LRRK2. In addition, this study will help understand …
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MJFF Heads to Neuroscience 2018 Conference
November 1, 2018
… this weekend in San Diego? Staff and funded investigators from The Michael J. Fox Foundation will be presenting … can visit us every day at Booth #4216 in the exhibit hall to learn about our funding opportunities and other resources … 4, 1:00 pm Nanosymposium 189: LRRK2 Mechanisms, Targets, and Pathways . Multiple sessions . Sunday, November …
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Overcoming obstacles to repurposing for neurodegenerative disease
June 24, 2014
… may offer an accelerated pathway for new treatments to patients but is also fraught with significant commercial, regulatory, and reimbursement challenges. The … diseases. Here, we present opportunities on how philanthropy, industry, and government can begin to …
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News in Context: Progress of “Long Sought Blood Test for Alzheimer’s”
July 28, 2020
… Today, The New York Times reported that a blood test to … Sweden measured a form of the protein tau — which clumps together in Alzheimer’s — in blood plasma. Their test … scans and spinal fluid tests for tau allowed scientists to compare results from the blood test. MJFF is supporting …
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Bitopertin to Alleviate Dyskinesia in Parkinson's Disease
… therapies for dyskinesia are only partly effective to alleviate the abnormal movements, and dyskinesia remains … diminish the severity of dyskinesia. Study Design: We will test the effect of the drug in an experimental model of … of our novel therapeutic paradigm. Following positive outcomes, we aim to further characterize the effect of our new …
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Rock Show to Benefit Team Fox!
January 4, 2012
… $65 and include dinner with carving and pasta stations, vegetables, salad and desserts! Open bar is from 7-8PM! For …