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Consortium to Develop an Alpha-synuclein Imaging Agent
… goal of this project is develop a positron emission tomography (PET) radiotracer to image the distribution of … biomarker that could be used for diagnosis (potentially pre-symptomatic), drug development, and monitoring of … including two academic groups, a radiopharmaceutical company, and a contract research organization. They sought …
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Harnessing the ADAR Protein to Repair the LRRK2 Mutation Causing Parkinson's Disease
… encodes the LRRK2 protein. The mutation, which changes a G to an A, produces a hyperactive variant of the LRRK2 … the mutated sequence and recruit a protein called ADAR, present in human cells, to perform the repair. Hypothesis: … will be tested in cells derived from people with PD, where we will assess whether these ASOs can decrease the …
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4 Smartphone Apps to Help You Manage Parkinson’s
January 25, 2013
… Tied to your smartphone? Put that data contract to good use. We asked our communities on Facebook and Twitter for advice on what … Twitter follower Rod. UnBlock Me is a similar puzzle game where you try to move a red block out of the center of the …
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Bringing the Team Fox Family Together with Some Disney Magic
January 21, 2016
… Goofy Challenge (running the half and full marathon on back-to-back days). Each of the four races starts well before … Molina. Another fierce Fox runner was Lauren Everly, who completed the half with her mother. Together, they returned … Disney Marathon Weekend and other Team Fox athletic events visit the athlete landing page . Seth Manthey …
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Going Beyond for LRRK2: An Interview with Grantee Sebastian Mathea
January 10, 2019
… ISS Commander Alex Gerst. Photo courtesy of NASA. This weekend, the results of an … (ISS). While the work in space is extraordinary, it represents one part of a much larger journey. Sebastian … trial and error, with many parameters to modify. You're testing hundreds of solutions to find the right one to grow …
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Scoring Parkinson's with Smartphone Apps and Wearable Devices
April 13, 2018
… Studies are taking steps toward giving Parkinson's patients, doctors and researchers … collected through a smartphone app. Nearly 130 participants completed tasks (e.g., making a vocal sound, finger tapping) … , used the PKG to measure motor scores relative to a predefined target range. If out of target range, the doctors …