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Target Validation Studies for the Discovery of Novel Small Molecule Therapeutics with the Potential to Modify Disease Outcome by Inhibiting Bacterial Amyloid Protein-induced Alpha-synuclein Aggregation and Associated Neuronal Toxicity
… disease frequently report serious gastrointestinal (GI) symptoms, most commonly constipation, which are not well treated with … to short-circuit the alpha-synuclein accumulation process, preserve healthy enteric nervous system function, and …
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Make Your Voice Heard: Urge Congress to Support PD Research
August 9, 2016
… representatives have returned to their home districts to visit their constituents. This is an ideal time to contact … and let them know what issues matter to the Parkinson's community. Below you'll find updates on several important … this process, the House and Senate are deciding whether and where to increase or decrease federal spending. The National …
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Contribute to Parkinson's Research through Exercise Clinical Trials
November 17, 2011
… With Thanksgiving and the holidays fast approaching, we want to highlight a few exercise trials that are currently … in this study are recruiting PD volunteers to study outcomes based on participation in physical therapy sessions, … information, and to contact the trial team, click here . Visit Fox Trial Finder to update your profile or find other …
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Partnering Program Works to Accelerate Parkinson’s Drug Development
January 29, 2014
… Research projects from three biopharmaceutical companies in the United States comprise the 2013 second half … participants’ research projects are presented directly to industry groups who may wish to invest in further … MJFF awardees chosen for the Partnering Program thus far, visit the Partnering Program Web page. Kimberly Sawicki …
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Method to Quantify Parkinsonian Motor Signs for Interventional Drug Trials
… Study Rationale: Current methods to evaluate motor impairments in Parkinson’s disease rely on … by monitoring natural interactions with a keyboard (on a computer or smart device). This approach provides a window … newly diagnosed Parkinson's disease patients who are prescribed dopaminergic medication by their neurologist. …
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Access to Clinical Data and Biospecimens, and Funding to Use Them, from The Michael J. Fox Foundation Encourages Drug Development
July 17, 2013
… announced that qualified researchers may now request access to clinical data and biospecimens from a collection of … in the late 1980s, and a long-term study on the effect of deprenyl and tocopherol (a form of vitamin E) on the … would benefit all PD patients, including those with more common, idiopathic forms of the disease. While requests for …