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Sugars Cause Alpha-Synuclein to Form Less-Toxic Clumps
… people with Parkinson's disease (PD). Chemicals that stick to alpha-synuclein make it toxic to brain cells. Sugar-like … clump differently. We will now simultaneously determine how this modification changes the fine structure of the … of Parkinson's Disease: We believe that the outcomes of this study will expand our knowledge in two …
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RaceTrac’s Longstanding Legacy of Giving Back to Speed a Parkinson’s Cure
November 17, 2022
… For RaceTrac, a third-generation family-owned company, its partnership with The Michael J. Fox Foundation … family, several RaceTrac employees, their families and customers are impacted by the disease in some way. “RaceTrac … The Michael J. Fox Foundation is a wonderful way to come together to support our community,” she says. In the past 11 …
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MJFF Funding Deep Brain Stimulation Registry to Improve Patient Outcomes
February 19, 2019
… stimulation (DBS), a surgical treatment for Parkinson’s symptoms, can be extremely effective to lessen symptoms and … when the best time is to consider this surgery and if and how it may affect their mood or personality. Learn more … patients perform with this surgery and why they have the outcomes they do. DBS is a great therapy and helps many …
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A Meta-Analysis of Single Nucleus Allele Specific Expression to Investigate Parkinson's Disease
… Rationale: We will study “allele-specific expression” to understand how DNA variants relevant to Parkinson’s disease impact the … it on all available Parkinson’s disease human datasets, and combine the results to better understand the disease. …
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Rigorous Research Creates Scientific Tools to Advance Parkinson's Therapies
January 12, 2018
… about disease and developing new treatments takes the right tools. The Michael J. Fox Foundation works with leading … to explore Parkinson's and create therapies. A recent commentary piece in Biochemical Journal profiles "the latest … linked them to the LRRK2 protein . LRRK2 is a priority target for our field because mutations in the gene that make …
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Ask the MD: Stimulating the Brain to Treat Parkinson’s
August 22, 2022
… Brain cells talk to each other using chemicals and electricity. Through this “discussion,” the brain directs how we think, feel, move and more. Changes in chemicals and … as “deep” into the brain as DBS does. How NIBS works is not completely understood. But experts believe it might help …