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Toward an Atlas of Endolysosomal System Dysfunction with PD-associated Channels/Transporters
… risk genes for Parkinson’s disease. These proteins function to transport protons and polyamines through the lysosomal … may be further regulated by the calcium channel TRPML1. Precisely how these proteins alter lysosomal health remains … and such an understanding can also provide a platform for testing the biological activity of small molecule activators …
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Five Ways to Speed a Cure This Summer
June 21, 2018
… Summer has officially arrived! And, to celebrate, we've rounded up the top five ways that you can make the most of the longer days and warmer months with Team Fox . Whether you hike, bike, mix and mean … networking with like-minded 20- and 30-somethings in your community. From Toronto to San Francisco, the Team Fox Young …
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Updated: Foundation Statement on Activities Related to Nilotinib for Parkinson's Disease
August 30, 2016
… [Updated: September 6, 2016] The Boston Globe published a letter to the editor from our CEO, … Michael J. Fox Foundation (MJFF) is aware of a broadly misrepresentative media report on our actions related to the … people with PD. The Foundation is not developing nilotinib commercially and holds no financial stake in the drug. …
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Spread Holiday Cheer with Team Fox Portion of Proceeds Gift Ideas
December 12, 2017
… season, Team Fox members are putting their business savvy to work in order to speed a cure for Parkinson's disease (PD). Many members of our community are using portion of proceeds sales to engage … are many unique ways you can support Parkinson's research! Visit teamfox.org for more information and to get …
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Alpha-synuclein Aggregation Leads to Loss of Functional Forms of the Protein and Toxicity
… The protein alpha-synuclein has been linked to Parkinson’s disease (PD). The prevailing hypotheses state that this protein is directly … is considered a viable therapeutic option. However, we have compelling evidence that show that alpha-synuclein is …
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Podcast: A Tool to Manage Tremor and Isolation
January 6, 2016
… Parkinson’s disease can be isolating. Movement and non-motor symptoms alike can lead people to disengage from their families, their social circles and their community. That isolation can be detrimental to one’s sense … disease. Learn more about Liftware . Maggie Kuhl Vice President Patient Engagement …