… encodes the LRRK2 protein. The mutation, which changes a G to an A, produces a hyperactive variant of the LRRK2 … the normal function of the brain cells and ultimately leads to PD. Recently, we developed a new way to repair G-to-A … of efficiently repairing the LRRK2 G2019S mutation by testing hundreds of thousands of different ASOs in human …

… based on the individual’s own response,” said Jamie Hamilton, PhD, senior associate director of research programs at … is not right for everyone. In the podcast, Jamie explains how MJFF is expanding DBS research to better understand the … our Ask the MD video on the topic . Kristina Magana Communications Officer …

… Objective/Rationale:  Dyskinesia is a term used to describe involuntary movements that develop as side … can interrupt smooth coordinated movements, affect communication and disrupt activities of daily living. … Disease: The purpose of this research study is to see how taking the study drug (topiramate or placebo), along …

… Fall Foliage Half Marathon and 5k will be held on Sunday, October 14, in the beautiful Hudson Valley town of Rhinebeck, NY. Marathon season is coming up (I’m talking to you NYC Marathon runners!) and … before the big day in November. So if you are interested in getting some real race experience (the clock, the crowds), …

… health and disease, like Parkinson’s. It holds a large community of bacteria (the microbiome) and a large network of nerves, second in number to the brain. And it’s in regular conversation with the … — has an impact on your brain.  These connections explain how Parkinson’s can cause gut symptoms, such as …

… Medical Association backs us up. A long list of investigators looked at more than 1,000 clinical trials (not just PD ones) approved by six ethics committees spread across France, Switzerland and Canada. Of … (9.9) of all the studies in this analysis (101/1,017) were stopped because they didn’t have enough volunteers. Trials …