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Cell-to-Cell Transport of Alpha-Synuclein
… This grant builds upon the research from a prior grant: The Transfer of … the model brain and analyze protein transference. Impact on Diagnosis/Treatment of Parkinson’s Disease: … Research Grant …
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Effect of Novel Neuronal Nicotinic Receptor Compounds on Treatment of Levodopa-induced Dyskinesia in Parkinson's Disease
… This grant builds upon the research from a prior grant: Prospective study of … assessment of its therapeutic potential. Importance of This Research for the Development of a New PD Therapy: The … Research Grant …
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LRRK2 Safety Initiative
… This grant builds upon the research from a prior grant: Pre-clinical Safety Study of … lungs, will be evaluated for any abnormalities. Impact on Diagnosis/Treatment of Parkinson's disease: These … Research Grant …
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Increasing Glucocerebrosidase Activity as a Therapeutic Strategy
… these small molecule drugs in disease models. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Previous research supports the notion that increasing … Research Grant …
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Testing Effects of Improved Levodopa Delivery with Dexterity and Gait Objective Measures
… the effectiveness of the two treatments. In addition, researchers will collect UPDRS data every hour. The OPDM … and carbidopa will be determined. Another aspect of this research will provide comparison between two controlled release levodopa products. Relevance to Diagnosis/Treatment of Parkinson’s Disease: As stated …
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Identification of Small Molecule Activators of Parkin Protein
… to exist in an “on” and “off” state. The goal of this research project is to identify small molecules that will … models of PD, and ultimately, humans. Relevance to Diagnosis/Treatment of Parkinson’s Disease: Development of a … for drug development, as well as tool compounds for research purposes. Studies with these compounds may not only …