… upon the research from a prior grant: Development of SHG to Discover Drugs to Selectively Block AlphaS toxicity Promising Outcomes of Original Grant : The goal of our original funded … grant was to use our alpha-synuclein assay to identify compounds that prevent conformational change to the fully …

… are calling on the Environmental Protection Agency (EPA) to ban paraquat, a widely used herbicide linked to the development of PD. Every 15 years, the EPA reviews all herbicides to ensure they comply with federal safety standards. In a letter sent to …

… drugs through a small plastic tube or needle placed into the target area of the brain. Unfortunately, the … of the drug must be injected into the brain and the drug comes into contact with normal brain tissue where it may … be used safely in the brain. We have completed experiments showing that they are safe to use in the brain. Our data show …

… Rationale: Amyloid fibrils play a key role in Parkinson's disease (PD). Studying their formation from self‐assembled … help aid the development of a valuable diagnostic tool. Despite progress in understanding these processes in a test … of sensitivity. We will synthesize a novel sensor type where the molecular container can trap xenon or …

… In Parkinson's patients a substantial number of dopaminergic neurons necessary for proper motor control have died, leading to dyskinesias that make it … capacity to sense, integrate and digest information and to command and execute movement. "Miswirings" can be worse than …

… of proteins such as alpha-synuclein in the brain. To diagnose PD, it is important to be able to detect such … and monitoring of disease progression, as well as more targeted treatment for individuals with these disorders.   Next … an academic university research group and a pharmaceutical company. The participation of a large company from the start …