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Using External Research Experts to Mine the 23andMe Parkinson’s Dataset
… resource for research in PD. Our main objective is to perform detailed analysis of this data to further clarify … and augment them by performing additional analysis. A comprehensive view of genetic risk in PD will, in the … more accurate diagnosis and, eventually, individually targeted treatment approaches. Anticipated Outcome: We expect …
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Measuring Lipids in iPSC-derived Dopamine Neurons to Identify Parkinson’s Biomarkers
… with Parkinson’s disease (PD). Lipids have the potential to be important biomarkers for PD, but the lack of … Hypothesis: We will determine if the analysis of the lipid composition of human dopamine neurons affected in PD can … a high-throughput assay already available in our lab to comprehensively characterize the lipid composition of human …
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Steve Gorny plans to "B.R.E.A.K. Parkinson's" By Running Entirely Across Kansas
May 16, 2012
… 17 marathons, one 50K run (31 miles), a 100 miler and a Tough Mudder (extremely hard adventure/obstacle course … to the northern border with Nebraska. His plan is to complete the 233 miles in just 5 days, looking to average 50 … that, Steve will be on the road solo – but is always up for company if you are in the area! To date, Gorny has raised …
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Tips for Parkinson's First Team Fox Event to Cross $1M Mark
June 20, 2014
… member Susan Bilotta — became the first Team Fox event to cross the $1M mark. With over 625 guests in attendance to … success. As guest bartending teams enthusiastically competed for drink sales and tips, guests bid on auction … to over $1.2 million. A huge congratulations to Susan, her committee and all the bartending teams and guests involved. …
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Podcast: Dave Iverson & Dr. Todd Sherer: New Approaches to Treating Dyskinesia
February 7, 2012
… Dyskinesia refers to the excessive and uncontrollable movements that are a … Fox Foundation CEO Dr. Todd Sherer about the Foundation’s commitment to identify and drive forward promising drug targets to reduce levodopa-induced dyskinesias (LID) in people …
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Development of a Sensitive Assay to Correlate LRRK2 Kinase Activity and Conformational State
… It appears that the kinase activity of LRRK2 is linked to its ability to self-associate. We have developed an assay … whether it is present alone (as a monomer) or in a large complex with multiple LRRK2 molecules, and then directly … assess these different activities of LRRK2 in parallel, and how they correlate with its ability to self-associate, since …