… Study Rationale:  This effort aims to produce foundational data that will provide immediate … Hypothesis:  We hypothesize that systems-based approaches, combined with complex genetics, will provide critical … characterization of these cells will provide a map of how the various genetic changes linked to PD interact at the …

… Objective/Rationale :  Our general objective is to investigate the role of a specific component of a cellular stress responses linked to organelle … alpha-synuclein and other genetic forms of PD. In this target validation project we aim to define the contribution of …

… Objective/Rationale: Mutations in LRRK2 cause the most common familial forms, and some sporadic forms, of … disease. Considerable evidence indicates that the neurotoxicity of these LRRK2 mutations correlates with … structural mechanisms drive kinase hyperactivation and how to modulate and inhibit LRRK2 GTPase and kinase …

… 22, 2014 - National Parkinson's organizations are working together to help provide Parkinson's patients and caregivers … to fuel mind and body. "The Davis Phinney Foundation is committed to empowering the Parkinson's community to take a … with Parkinson's disease to live well today. It also shows the community our organizations' shared commitment to …

… You don’t need a time machine to learn more about the origin story of The Michael J. Fox … I always feel that if you flip the coin 100 times, you're going to come up heads 51.” Get your daily dose of inspiration by …

… NY — The Michael J. Fox Foundation for Parkinson’s Research today announced nearly $1.1 million for projects aimed at … to drive tangible progress, MJFF is also supporting a comprehensive biomarker discovery and verification effort, … today, the alpha-synuclein and DJ-1 assays will also be tested as part of PPMI. For more information on these …