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Results from a phase I safety trial of hAADC gene therapy for Parkinson disease
May 20, 2008
… infusion of an adeno-associated viral (AAV) vector containing the human aromatic l-amino acid decarboxylase … of a phase I safety trial. Here we report the findings for the first cohort of five patients. Methods: Patients … the AADC tracer, 6-[18F]fluoro-l-m-tyrosine (FMT), were performed at baseline and at 1 and 6 months after infusion as …
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In Case You Missed It: Tax Break for Charitable Donations Made from IRAs
December 24, 2014
… Congress just passed a last-minute tax break on charitable donations from Individual Retirement Accounts (IRA) for those over 70½. If you have an IRA, you may be eligible to make a gift directly … With just a few days left in 2014, consider the role you can play in progress toward a cure for Parkinson’s disease. …
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Potential Parkinson's Therapy Secures $23 Million for Testing from NIH after Foundation Funding
March 31, 2014
… for Parkinson's Research (MJFF) have enabled researchers to secure a $23 million grant from the National Institutes of … Parkinson's progression. The trial investigating the compound isradipine will be the most advanced, current study … D. James Surmeier, PhD , also of Northwestern University, looking at the compound's neuroprotective effects in PD …
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DNA Methylation Profiling from Blood as a Source for Biomarker Discovery in Parkinson’s Disease
… Project Description: In this study we will compare the DNA methylation patterns from cells isolated … might serve as an early diagnostic tool. Anticipated Outcome: We hope to generate a very detailed map of … PD manifestations to aid in clinical diagnosis. Final Outcome DNA methylation is a mechanism that cells use to turn …
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Neurology Today Profiles PPMI Co-Principal Investigator Carlie Tanner: “You couldn’t ask for more from a scientific career.”
May 24, 2021
… Carlie Tanner, MD, PhD, professor of neurology at the Weill Institute for Neurosciences, University of California, San Francisco. Earlier this month, co-principal investigator of our landmark Parkinson’s … is this realistic possibility that we may be able to overcome this condition. It’s not just dreaming. We may …
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Swimming Away from Parkinson's
August 29, 2012
… relations consultant and freelance writer living in Boston. His wife has Parkinson's. Paul offers a moving account … about the same time; although by different paths. I was coming off a hip replacement operation and was looking for … am Leander to her Hero, and as wonderful as our daily swims make us feel I cannot help but reflect on what brought us to …